Results 81 to 90 of about 5,673 (157)

Autophagy activation by urolithin-a derivative UA-36 mitigates Friedreich's ataxia pathologies induced by frataxin deficiency. [PDF]

Mol Biomed
Gong Q, Liu T, Han X, Zhang R, Liu X, Xiong B, Ali T, Huang J, Xie Y, Li S, Yang X.   +10 more
europepmc   +1 more source

Multi-omics Mendelian randomization integrating GWAS, eQTL, mQTL and pQTL data prioritizes mitochondrial gene <i>FXN</i> as a hypothesis-generating candidate for nephrolithiasis. [PDF]

Front Immunol
Wu Y, Ye S, Li P, Wu Z, Guo Z, Bian J, Sheng M, Lai D.   +7 more
europepmc   +1 more source

Mitochondrial iron overload is associated with lysosomal dysfunction-mediated mitophagy impairment in the heart of Friedreich's ataxia. [PDF]

Mitochondrion
Jee E, Medha M, Baek H, Kim J, Kim Y.
europepmc   +1 more source

Autophagy at the Crossroads of Protein and RNA Toxicity in Repeat Expansion Cerebellar Ataxias. [PDF]

Cells
Tortoriello S, Rossi S, Della Valle I, D'Ambrosi N, Cozzolino M.   +4 more
europepmc   +1 more source

Targeting rare splicing defects: Antisense oligonucleotides offer a therapeutic strategy in FRDA. [PDF]

Mol Ther Nucleic Acids
Kerkhof LMC, Buijsen RAM.
europepmc   +1 more source

Serial assessment of echocardiographic measures in Friedreich ataxia. [PDF]

Am Heart J Plus
Lynch DR, Keita M, Gunther K, Park C, Schadt K, Mercer-Rosa L, Lin KY.   +6 more
europepmc   +1 more source

Modeling Friedreich's ataxia with Bergmann glia-enriched human cerebellar organoids. [PDF]

Commun Biol
Ryu S, Inman J, Hong H, Jovanovic VM, Chen Q, Gedik Y, Jethmalani Y, Hur I, Harouni M, Voss T, Lack J, Collins J, Ormanoglu P, Simeonov A, Tristan CA, Singeç I.   +15 more
europepmc   +1 more source

Safety and efficacy of individualised exercise and NAD⁺ precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial. [PDF]

Lancet Neurol
Lin KY, Bucha A, McSweeney K, Wade KL, Karaj A, Tamaroff J, O'Malley S, Chung NM, Cilenti NA, Wanner J, Adzika GK, Mesaros C, Blair IA, Rojsajjakul T, Serai S, Farmer J, Bryant K, Lu Y, Harhay MO, Weber DR, Paridon SM, Seifert EL, Putt ME, Zamani P, Baur JA, Lynch DR, McCormack SE.   +26 more
europepmc   +1 more source

Evaluation of Mitochondrial Complex 1 Density with [¹⁸F]BCPP-EF in a Murine Model and Individuals with Friedreich Ataxia. [PDF]

J Nucl Med
Chen L, Rizzo G, Bulawa C, Van Dijk KRA, Henning EC, Martelli A, Palmer J, McIntosh A, Pregel M, Sun P, Adewunmi E, Aldridge M, Chan J, Gunn RN, Huiban M, Listanco A, Loudon PT, Moz S, Passchier J, Sauvage L, Stewart R, Wells L, Rabiner EA, Charnas LR, Festenstein RJ.   +24 more
europepmc   +1 more source

Comparative Structural Analysis of Escherichia Coli Cyay at Room and Cryogenic Temperatures Using Macromolecular and Serial Crystallography. [PDF]

Chembiochem
Shafiei A, Baldir N, Na J, Kim JH, DeMirci H, DeMirci H.   +5 more
europepmc   +1 more source