Results 21 to 30 of about 27,457 (261)

Structural enzymology using X-ray free electron lasers

open access: yesStructural Dynamics, 2017
Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals are mixed with a substrate just prior to being probed by an X-ray pulse. This approach offers several advantages over
Christopher Kupitz   +49 more
doaj   +1 more source

Bayesian Optimization of a Free-Electron Laser

open access: yesPhysical Review Letters, 2020
6 pages, 3 ...
J. Duris   +10 more
openaire   +4 more sources

Free electron lasers using ‘beam by design’

open access: yesNew Journal of Physics, 2015
Several methods have been proposed in the literature to improve free electron laser output by transforming the electron phase-space before entering the FEL interaction region.
J R Henderson   +2 more
doaj   +1 more source

High average current electron guns for high-power free electron lasers

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2011
High average power free-electron lasers (FELs) require high average current electron injectors capable of generating high quality, short duration electron bunches with a repetition rate equal to the frequency of the rf linac.
Phillip Sprangle   +6 more
doaj   +1 more source

Recirculated Wave Undulators for Compact FELs

open access: yesApplied Sciences, 2021
Particular schemes of Free Electron Lasers (FELs) are designed to exploit wave undulators. We consider a system employing a recirculated electromagnetic undulator provided by a high-power laser in a resonator cavity.
Alessandro Curcio
doaj   +1 more source

Limitations of electron beam conditioning for free-electron lasers

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2003
Several ideas have been proposed to “condition” an electron beam prior to the undulator of a free-electron laser (FEL) by increasing each particle’s energy in proportion to the square of its transverse betatron amplitude.
P. Emma, G. Stupakov
doaj   +1 more source

Vacuum birefringence at x-ray free-electron lasers

open access: yesNew Journal of Physics, 2021
We study the perspectives of measuring the phenomenon of vacuum birefringence predicted by quantum electrodynamics using an x-ray free-electron laser (XFEL) alone.
Felix Karbstein   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Pulse Duration of Seeded Free-Electron Lasers

open access: yesPhysical Review X, 2017
The pulse duration, and, more generally, the temporal intensity profile of free-electron laser (FEL) pulses, is of utmost importance for exploring the new perspectives offered by FELs; it is a nontrivial experimental parameter that needs to be ...
Paola Finetti   +45 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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