Results 31 to 40 of about 27,391 (261)

Pulse Duration of Seeded Free-Electron Lasers

Physical Review X, 2017
The pulse duration, and, more generally, the temporal intensity profile of free-electron laser (FEL) pulses, is of utmost importance for exploring the new perspectives offered by FELs; it is a nontrivial experimental parameter that needs to be ...
Paola Finetti, Hauke Höppner, Enrico Allaria, Carlo Callegari, Flavio Capotondi, Paolo Cinquegrana, Marcello Coreno, Riccardo Cucini, Miltcho B. Danailov, Alexander Demidovich, Giovanni De Ninno, Michele Di Fraia, Raimund Feifel, Eugenio Ferrari, Lars Fröhlich, David Gauthier, Torsten Golz, Cesare Grazioli, Yun Kai, Gabor Kurdi, Nicola Mahne, Michele Manfredda, Nikita Medvedev, Ivaylo P. Nikolov, Emanuele Pedersoli, Giuseppe Penco, Oksana Plekan, Mark J. Prandolini, Kevin C. Prince, Lorenzo Raimondi, Primoz Rebernik, Robert Riedel, Eleonore Roussel, Paolo Sigalotti, Richard Squibb, Nikola Stojanovic, Stefano Stranges, Cristian Svetina, Takanori Tanikawa, Ulrich Teubner, Victor Tkachenko, Sven Toleikis, Marco Zangrando, Beata Ziaja, Franz Tavella, Luca Giannessi   +45 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Free electron laser.

The Review of Laser Engineering, 1987
Concepts and historical review of free electron laser are reported. Since the experiment at Stanford University was successful in 1977, great numberof FEL experiments with various accelerators were successfully performed to observe amplification and oscillation of radiations in the wavelength range of 0.5 μm-103μm.
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Laser phase errors in seeded free electron lasers

Physical Review Special Topics. Accelerators and Beams, 2012
Harmonic seeding of free electron lasers has attracted significant attention as a method for producing transform-limited pulses in the soft x-ray region. Harmonic multiplication schemes extend seeding to shorter wavelengths, but also amplify the spectral
D. Ratner, A. Fry, G. Stupakov, W. White
doaj   +1 more source

The Oxford free electron laser project

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1990
It is proposed to use the Oxford 10 MV Van de Graaff accelerator as an electron beam source for a free electron laser (FEL) operating in the far infra red (FIR). The configuration and layout of the Van de Graaff make it very suitable for conversion, with a potentially high efficiency for electron beam recovery. Using a 2 m long wiggler of 34 mm period,
Allison, W, Brau, C, Brooks, C, Doucas, G, Elgin, J, Gillespie, W, Holmes, A, Jaroszynski, D, Kimmitt, M, Martin, P, Mulvey, J, Pidgeon, C, Poole, M   +12 more
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Real-time tracking of the intramolecular vibrational dynamics of liquid water

Communications Chemistry
Water’s polarity and hydrogen-bond network give rise to its unique chemical and biochemical behaviour. Its vibrational motions, occurring on a few-femtosecond timescale, govern ultrafast energy transfer within the hydrogen-bond network.
Gaia Giovannetti, Sergey Ryabchuk, Ammar Bin Wahid, Hui-Yuan Chen, Giovanni Batignani, Erik P. Månsson, Oliviero Cannelli, Emanuele Mai, Andrea Trabattoni, Ofer Neufeld, Angel Rubio, Vincent Wanie, Hugo Marroux, Tullio Scopigno, Majed Chergui, Francesca Calegari   +15 more
doaj   +1 more source

Formation of electron bunches for harmonic cascade x-ray free electron lasers

Physical Review Special Topics. Accelerators and Beams, 2006
Specific requirements for the electron beam in harmonic cascade-free electron lasers, together with means to produce such beams, are presented. All results are illustrated with simulations and particle tracking studies.
M. Cornacchia, S. Di Mitri, G. Penco, A. A. Zholents   +3 more
doaj   +1 more source

Radio-Frequency Undulators, Cyclotron Auto Resonance Maser and Free Electron Lasers

Applied Sciences, 2021
We discuss a hybrid Free Electron Laser (FEL) architecture operating with a RF undulator provided by a powerful Cyclotron Auto-Resonance Maser (CARM). We outline the design elements to operate a compact X-ray device.
Emanuele Di Palma, Silvio Ceccuzzi, Gian Luca Ravera, Elio Sabia, Ivan Spassovsky, Giuseppe Dattoli   +5 more
doaj   +1 more source