Results 51 to 60 of about 140,342 (289)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Bound-free $\mathbf{e}^+ \mathbf{e}^-$ pair creation with a linearly polarized laser field and a nuclear field

open access: yes, 2008
The process of bound-free pair production of electrons and positrons in combined laser and Coulomb fields is investigated. It is assumed that an ion collides at relativistic speed with an intense x-ray laser beam of linear polarization.
Deneke, C., Müller, C.
core   +1 more source

Photoionization experiments with the ultrafast EUV laser 'FLASH' - free electron laser in Hamburg [PDF]

open access: yes, 2007
The advent of mirror-less Free Electron Lasers emitting polarised and coherent 'laser-like' beams of high peak (> 1GW) and average (up to 100mW) powers in the extreme-UV (EUV) and X-ray bands of the electromagnetic spectrum heralds a new era in the study
Costello, John T.
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

High efficiency tapered free-electron lasers with a prebunched electron beam

open access: yesPhysical Review Accelerators and Beams, 2017
In this paper we analyze the high gain, high efficiency tapered free-electron laser amplifier with a prebunched electron beam. Simple scaling laws are derived for the peak output power and extraction efficiency and verified using 1D simulations.
C. Emma   +4 more
doaj   +1 more source

Compression of extreme-ultraviolet ultrashort pulses by grating configurations [PDF]

open access: yes, 2015
The design and realization of grating instruments to condition the spectral phase of ultrashort extreme-ultraviolet pulses are discussed. The main application of such configurations is the temporal compression of pulses by compensating the phase chirp ...
Frassetto, Fabio   +2 more
core   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Thermoreflectance Detection of Point Defects Resulting from Focused Ion Beam Milling

open access: yesAdvanced Engineering Materials, EarlyView.
Focused ion beam (FIB) milling is a common tool for nanoscale material processing, however irradiation damage, redeposition, and contamination can occur. We use several characterization tools to show FIB‐induced effects beyond 1 mm from the milled area.
Thomas W. Pfeifer   +3 more
wiley   +1 more source

Prevailing features of X-ray induced molecular electron spectra revealed with fullerenes

open access: yes, 2014
Intense X-ray photo-absorption from short and intense pulses by a molecule triggers complicated electron and subsequently ion dynamics leading to photo-electron spectra which are difficult to interpret.
Garibay, Abraham Camacho   +2 more
core   +1 more source

Low‐Cost, Large‐Scale Nanoporous Metals by Mechanical Alloying, Oxide Reduction, and Dealloying of Powders

open access: yesAdvanced Engineering Materials, EarlyView.
Powder metal processing provides scalable advantages in nanoporous (np) metal development. Mechanical alloying is used to produce unique precursors for hybrid nanopore formation by oxide reduction and dealloying. As demonstrated in np Ag, this approach improves process efficiency while promoting smaller ligaments and larger pores, both of which are ...
Mark A. Atwater, Oliver A. Fowler
wiley   +1 more source

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