Results 41 to 50 of about 27,457 (261)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

High efficiency tapered free-electron lasers with a prebunched electron beam

Physical Review Accelerators and Beams, 2017
In this paper we analyze the high gain, high efficiency tapered free-electron laser amplifier with a prebunched electron beam. Simple scaling laws are derived for the peak output power and extraction efficiency and verified using 1D simulations.
C. Emma, N. Sudar, P. Musumeci, A. Urbanowicz, C. Pellegrini   +4 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

The Oxford free electron laser project

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1990
It is proposed to use the Oxford 10 MV Van de Graaff accelerator as an electron beam source for a free electron laser (FEL) operating in the far infra red (FIR). The configuration and layout of the Van de Graaff make it very suitable for conversion, with a potentially high efficiency for electron beam recovery. Using a 2 m long wiggler of 34 mm period,
Allison, W, Brau, C, Brooks, C, Doucas, G, Elgin, J, Gillespie, W, Holmes, A, Jaroszynski, D, Kimmitt, M, Martin, P, Mulvey, J, Pidgeon, C, Poole, M   +12 more
openaire   +2 more sources

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth, Tomáš Babinský, Jan Lars Riedel, Wen Hao Kan, Aijun Huang, Martin Heilmaier, Ivo Šulák   +6 more
wiley   +1 more source

Low‐Angle Grain Boundaries and Re‐Segregation in Single‐Crystalline Ni‐Base Superalloys

Advanced Engineering Materials, EarlyView.
This work demonstrates that Re‐segregation at low‐angle grain boundaries (LAGBs) in Ni‐base superalloys is influenced by misorientation angle. Advanced microscopy and atom probe tomography reveal that higher misorientation angles increases Re‐segregation.
Alireza B. Parsa, Aparna Saksena, Alesander Kostka, Pascal Thome, Felicitas Scholz, Alexandre Mussi, Christoph Somsen, Baptiste Gault, Jan Frenzel, Gunther Eggeler   +9 more
wiley   +1 more source

Active FEL-Klystrons as Formers of Femto-Second Clusters of Electromagnetic Field. Description of Models on the Basis of Sections of ‘Ordinary’ FEL’: Analisys [PDF]

Журнал нано- та електронної фізики, 2011
Physical processes of ultrashort electromagnetic cluster formation in multiharmonic parametrical free electron lasers are analyzed. The conditions, which are necessary for formation of such clusters, are found out.
V.V. Kulish, A.V. Lysenko, A.Ju. Brusnik
doaj  

Model-based optimization of tapered free-electron lasers

Physical Review Special Topics. Accelerators and Beams, 2015
The energy extraction efficiency is a figure of merit for a free-electron laser (FEL). It can be enhanced by the technique of undulator tapering, which enables the sustained growth of radiation power beyond the initial saturation point.
Alan Mak, Francesca Curbis, Sverker Werin   +2 more
doaj   +1 more source

Minimum Spectral Bandwidth in Echo Seeded Free Electron Lasers

Frontiers in Physics, 2019
This paper examines the impact of non-linear longitudinal phase distortions on the spectral bandwidth in echo seeded free electron lasers (FELs). It extends the existing theory developed in Hemsing [1] for echo-enabled harmonic generation (EEHG) to ...
Erik Hemsing
doaj   +1 more source