Results 141 to 150 of about 11,868,774 (305)
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Vocal septet, Anniversary Party for Kids, Roseland Free Public Library (Roseland, N.J.)
Singers, Anniversary Party for Kids, Roseland Free Public Library (Roseland, N.J.)
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Check Written By the Friends of the Roseland Library to the Roseland Free Public Library
Copy of the check written in to the Roseland Free Public Library from the Friends ...
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Free spectral range of whispering-gallery (WG)-like modes in a two-dimensional (2D) square microcavity is found to be twice that in a 2D circular microcavity.
Guo, WH, Chinese Acad Sci, Inst Semicond, State Key Lab Integrated Optoelect, POB 912, Beijing 100083, Peoples R China. 电子邮箱地址: gwh@red.semi.ac.cn +4 more
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Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Columbus Free Press during Doo Dah Parade
Staff member of the Columbus Free Press with a float during the Doo Dah Parade in Columbus, Ohio. He stands at an ironing board with a sign reading "Press Corps." The Doo Dah Parade is a community event held on July 4th each summer since 1983, with its ...
Columbus Free Press (Publisher)
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Approach to creating an intelligent system for free-range livestock farming
The development of intelligent systems for the tracking of free-range livestock is a challenge to both information and communication technology (ICT) scientists and those in the animal sciences.
Todorka Glushkova +3 more
core +1 more source

