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Brain, 2023 Free-water imaging can predict and monitor dopamine system degeneration in people with Parkinson's disease. It can also enhance the sensitivity of traditional diffusion tensor imaging (DTI) metrics for indexing neurodegeneration. However, these tools are
Nicola J Ray +2 more
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Free water elimination and mapping from diffusion MRI
Magnetic Resonance in Medicine, 2009 Relating brain tissue properties to diffusion tensor imaging (DTI) is limited when an image voxel contains partial volume of brain tissue with free water, such as cerebrospinal fluid or edema, rendering the DTI indices no longer useful for describing the
Ofer Pasternak, Nir Sochen, Yaniv Gur
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Brain‐age estimation accuracy is significantly increased using multishell free‐water reconstruction
Human Brain Mapping, 2022 International audienceAlthough free-water diffusion reconstruction for diffusion-weighted imaging (DWI) data can be applied to both single-shell and multishell data, recent finding in synthetic data suggests that the free-water indices from single-shell ...
Federico Nemmi, Patrice Peran
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ISMRM Annual Meeting, 2023
We compared two free water methods, T2 relaxometry-based CSFF and DTI-based DTI-FW, by associating them with age, cognitive score RAVLT, amyloid beta deposition from PiB SUVr, tau deposition from MK6240, aqueduct CSF flow from PC-MRI and ventricle CSF clearance from MK-PET. Results show that CSFF outperforms DTI-FW in most relation pairs.
Liangdong Zhou, Thanh Nguyen, Yi Li
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We compared two free water methods, T2 relaxometry-based CSFF and DTI-based DTI-FW, by associating them with age, cognitive score RAVLT, amyloid beta deposition from PiB SUVr, tau deposition from MK6240, aqueduct CSF flow from PC-MRI and ventricle CSF clearance from MK-PET. Results show that CSFF outperforms DTI-FW in most relation pairs.
Liangdong Zhou, Thanh Nguyen, Yi Li
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B-value dependence of DTI quantitation and sensitivity in detecting neural tissue changes
NeuroImage, 2010 Recently, remarkable success has been demonstrated in using MR diffusion tensor imaging (DTI) to characterize white matter. Water diffusion in complex biological tissue microstructure is not a free or Gaussian process but is hindered and restricted, thus
Edward S Hui +2 more
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ISMRM Annual Meeting
Major depressive disorder (MDD) is a common mental disease with unclear pathophysiology. Herein, we explored the differences in the whole-brain gray matter free-water axial diffusivity (AD) and mean diffusivity (MD) values between MDD patients and healthy controls using free-water DTI.
Xuecong Lin +9 more
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Major depressive disorder (MDD) is a common mental disease with unclear pathophysiology. Herein, we explored the differences in the whole-brain gray matter free-water axial diffusivity (AD) and mean diffusivity (MD) values between MDD patients and healthy controls using free-water DTI.
Xuecong Lin +9 more
openaire +1 more source
ISMRM Annual Meeting
The objective of this study was to explore the relationship between cognitive impairment and free-water elimination DTI (FWE-DTI) metrics in patients with intracranial vascular occlusion disease (IVOD) and transient ischemic attack (TIA). 22 IVOD with TIA patients were tested with cognitive scales and scanned using a 3T echo-planar imaging sequence ...
Siyuan Fang +5 more
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The objective of this study was to explore the relationship between cognitive impairment and free-water elimination DTI (FWE-DTI) metrics in patients with intracranial vascular occlusion disease (IVOD) and transient ischemic attack (TIA). 22 IVOD with TIA patients were tested with cognitive scales and scanned using a 3T echo-planar imaging sequence ...
Siyuan Fang +5 more
openaire +1 more source
ISMRM Annual Meeting
Motivation: The study aims to address the limitations of standard DTI in detecting subtle white matter alterations in individuals with mild cognitive impairment (MCI). Goal(s): Compare standard vs. free-water (fw) corrected tractography for MCI assessment.
Maurizio Bergamino +2 more
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Motivation: The study aims to address the limitations of standard DTI in detecting subtle white matter alterations in individuals with mild cognitive impairment (MCI). Goal(s): Compare standard vs. free-water (fw) corrected tractography for MCI assessment.
Maurizio Bergamino +2 more
openaire +1 more source
ISMRM Annual Meeting
Motivation: Diffusion tensor imaging in the spinal cord is compromised by partial volume effects from surrounding cerebrospinal fluid. Free-water elimination shows promise of partial volume effect reduction in the brain but has never been tested on the human spinal cord.
Alma Blombäck +3 more
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Motivation: Diffusion tensor imaging in the spinal cord is compromised by partial volume effects from surrounding cerebrospinal fluid. Free-water elimination shows promise of partial volume effect reduction in the brain but has never been tested on the human spinal cord.
Alma Blombäck +3 more
openaire +1 more source