Results 91 to 100 of about 9,409,646 (303)

Free Access to Primary Data Should Be a Right [PDF]

open access: yes
Few things are as important for development as the availability of data and unfettered access. Without data there can be no needs assessment. It will scarcely be possible to design effective policies or to implement, monitor and evaluate them.
Rafael Guerreiro Osorio
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

O óbvio da informação científica: acesso e uso

open access: yesTransinformação
O texto aborda o acesso e o uso da informação científica, a partir da sua concepção e função para o avanço científico e tecnológico dos países. Na sociedade contemporânea, as redes eletrônicas de comunicação (ênfase para a Internet) agilizam o fluxo ...
Maria das Graças Targino
doaj  

Aproximació al panorama actual de la reutilització de la informació del sector públic

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2012
A partir de les ponències de la II Jornada sobre la reutilización de la información del sector público, organitzada per les universitats Carlos III i Complutense de Madrid el febrer del 2012, s'analitza el marc legislatiu de la reutilització a Espanya ...
Valentín Ruiz, Francisco José   +1 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

La reutilització de la informació del sector públic a Espanya : una base sòlida per a un futur prometedor

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2012
La reutilització de la informació del sector públic és la base de les estratègies de dades obertes i de govern obert. Les autoritats europees fomenten polítiques de reutilització de la informació pública com un dels pilars de l'economia digital i una ...
García García, Emilio   +1 more
doaj   +1 more source

Decarboxylative Sulfinylation Enables a Direct, Metal-Free Access to Sulfoxides from Carboxylic Acids. [PDF]

open access: yesAngew Chem Int Ed Engl, 2022
Nguyen VD   +6 more
europepmc   +1 more source

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