Results 71 to 80 of about 19,018,457 (307)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The story of the Urbana Free Library : its early days.

open access: yes, 1949
On cover: "1874-1949 Diamond anniversary of the Urbana Free Library."Mode of access ...
Urbana Free Library.
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Columbus Free Press newsletter

open access: yes, 1978
Newsletter sent to Columbus Free Press staff and volunteers, documenting the current financial status of the newspaper and relevant news. The Columbus Free Press began as a bi-weekly publication in Columbus, Ohio, in 1970.
Columbus Free Press (Publisher)
core  

Alternative academic access - analising the success (part one) [PDF]

open access: yes, 2006
Published ArticleThe contemporary challenge facing all Higher Education Institutions (HEI's) since 1994 focuses on generating methods to broaden the access for schoolleavers who are ill-prepared and not ready for higher education.
Van den Berg, Andre
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

FREE ACCESS TO JUSTICE AND PROCEDURAL LIABILITY

open access: yesRevista Eletrônica de Direito Processual, 2018
The essay proposes a rational analysis of the procedural law wich grants free access to the legal system to those who can‟t afford it, proposing that the effects of the decision wich grants this benefit should be restricted in order to guarantee wide ...
Lucas Pahl Schaan Núñez
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Columbus Free Press subscription form

open access: yes, 1990
Order form encouraging subscription to and financial support for the Columbus Free Press. It also announces that the newspaper will no longer be available for free, but can be obtained by subscription or for $1 per copy at Free Press newsboxes.
Columbus Free Press (Publisher)
core  

Open and Free Access to Education for All [PDF]

open access: yes, 2020
Open education has evolved over time and now has different interpretations. Three main versions of open education are considered, namely open universities, open educational resources (OER) and MOOCs. These all aim to increase access to education, but have different approaches for realising this aim.
openaire   +1 more source

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