Results 101 to 110 of about 5,297,487 (306)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Amino acids as diagnostics of soil and soil water quality [PDF]

open access: yes, 2004
Information on the contribution of amino acids to dissolved organic nitrogen and carbon exported from grassland soil is scarce. Evidence from the literature for other environments, suggests that determination of amino acid patterns of distribution may be
Hawkins, J. M. B.   +1 more
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells

open access: yes, 2014
Background/aims: human embryonic stem cells (hESCs) are a potential source of cells for treatment of many degenerative diseases, but in culture have a propensity to spontaneously differentiate, possibly due to suboptimal conditions. Culture at low oxygen
Christensen, David R.   +5 more
core   +1 more source

Amino acid racemization dating: Method development using African ostrich (Struthio camelus) eggshell [PDF]

open access: yes, 2013
Ostrich eggshell (OES) is ubiquitous in archaeological sites in Africa and is a favoured substrate for amino acid racemisation (AAR) geochronology, yielding consistent results and thought to approximate a closed system with respect to protein diagenesis.
Crisp, Molly Katherine
core   +3 more sources

Towards the directed evolution of an L-aspartate oxidase from Pseudomonas putida [PDF]

open access: yes, 2012
Amino acid oxidases (AAOs) are enantioselective flavoenzymes that catalyse the oxidation of amino acids into imino acids, which spontaneously hydrolyse in water to form keto acids. AAOs have several potential applications, most notably as biocatalysts in
Leese, Charlotte
core   +2 more sources

Difference of Free Amino Acids in Different Primary Processed Yunnan Arabica Coffee and Its Taste Forming Mechanism

open access: yesShipin gongye ke-ji
To explore the influence of three different primary processing methods (wet-processed, honey-processed and sun-exposed processed) of Yunnan Arabica coffee on the free amino acid and its taste forming mechanisms, the total protein content, free amino ...
Ziqi GAO   +6 more
doaj   +1 more source

Assessment of seminal plasma free amino acids among fertile men

open access: yesSVU - International Journal of Medical Sciences, 2019
Background:Amino acids can elevate sperm count, motility, and morphology. Increasing the availability of these amino acids can help to improve male fertility certain foods can help to improve sperm parameters.
Marwa O. Aboelwafa *   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

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