Results 71 to 80 of about 59,031 (278)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Interlacing Families IV: Bipartite Ramanujan Graphs of All Sizes

, 2015
We prove that there exist bipartite Ramanujan graphs of every degree and every number of vertices. The proof is based on analyzing the expected characteristic polynomial of a union of random perfect matchings, and involves three ingredients: (1) a ...
Marcus, Adam W., Spielman, Daniel A., Srivastava, Nikhil   +2 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

PerSANet: Synergizing Multi-Scale Inception and Energy-Based Attention for Time Series Anomaly Detection

IEEE Access
Time series anomaly detection is a cornerstone of reliability in modern industrial systems and smart grids. While recent advancements, notably TimesNet, have achieved state-of-the-art performance by transforming 1D temporal sequences into 2D period ...
Jinheng Wang, Yuqi Zhao, Junchang Zheng, Yehao Feng, Linyan Wen, Hailin Huang, Yulin Wang   +6 more
doaj   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

TwinMixing: A shuffle-aware feature interaction model for multi-task segmentation

Results in Engineering
Accurate and efficient perception is essential for autonomous driving, where segmentation tasks such as drivable-area and lane segmentation provide critical cues for motion planning and control.
Minh-Khoi Do, Huy Che, Dinh-Duy Phan, Duc-Lung Vu, Duc-Khai Lam   +4 more
doaj   +1 more source

Free Convolution and the Random Sum of Matrices

Publications of the Research Institute for Mathematical Sciences, 1993
We show that the spectral measure of the sum of two selfadjoint matrices is 'almost surely' given by the free convolution (in the sense of Voiculescu) of the spectral measures of the two matrices if their size tends to infinity.
openaire   +3 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Polynomial convolutions in max-plus algebra [PDF]

, 2018
Recently, in a work that grew out of their exploration of interlacing polynomials, Marcus, Spielman and Srivastava and then Marcus studied certain combinatorial polynomial convolutions. These convolutions preserve real-rootedness and capture expectations
Lehner, Franz, Peperko, Aljosa, Rosenmann, Amnon   +2 more
core   +2 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source