Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
ASSESSING THE TEACHING EFFICACY BELIEFS OF SCIENCE TEACHERS IN SECONDARY SCHOOLS IN THE FREE STATE PROVINCE [PDF]
, 2013 Thesis (D. Phil. (Humanities)) -- Central University of Technology, Free State, 2013The purpose of this study was to assess the science teaching efficacy of the Physical Science teachers in the secondary schools of the Free State province of the Republic
Lekhu, Motshidisi. Anna.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Machine Learning and Deep Learning for Crop Disease Diagnosis: Performance Analysis and Review
AgronomyCrop diseases pose a significant threat to global food security, with both economic and environmental consequences. Early and accurate detection is essential for timely intervention and sustainable farming.
Habiba Njeri Ngugi +2 more
doaj +1 more source
Replication Data for: Fundamental scaling laws of water-window X-rays from free electron-driven van der Waals ...
Pramanik, Nikhil
core +1 more source
African women as effective managers in the Free State Provincial Government: addressing performance determinants [PDF]
, 2002 ThesisChange is a process which, although feared and resisted by many, is unfortunately often inevitable. South Africa, with all its diversity, was no exception, and had to experience its fair share of change with the quantum leap from an Apartheid ...
Lues, Liezel
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Contrast sensitivity perimetry data from adults free of eye disease
Data in Brief, 2016 This data article contains data referenced in “Individual Differences in the Shape of the Nasal Visual Field” [1]. The data were gathered from volunteers free of eye disease ages 21–85 who were tested with Contrast Sensitivity Perimetry (CSP), which uses
William H. Swanson +3 more
doaj +1 more source
The implementation of technology education in secondary schools in the Free State province (urban areas) [PDF]
, 2004 ThesisThe purpose of this study was to investigate the implimentation of Technology as a subject in schools and to determine the attitudes of educators towards Technology as a subject and Outcomes-Based Education in general. The main aim of this study
Heymans, Jacobus Hendrikus
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source