Results 121 to 130 of about 11,330,773 (285)
The Fourth Industrial Revolution – what does it mean to our future faculty?
Vukosi Marivate +4 more
doaj +1 more source
Analysis of plant metabolomics data using identification‐free approaches
Plant metabolomes are structurally diverse. One of the most popular techniques for sampling this diversity is liquid chromatography–mass spectrometry (LC‐MS), which typically detects thousands of peaks from single organ extracts, many representing true ...
Xinyu Yuan +2 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Research Advances in Free Cooling Technology of Data Centers
The increasing energy consumption of data centers attracts more and more attention, much of which is consumed by the cooling system. Utilizing efficient cooling methods is the urgent need for realizing emission control targets, and the free cooling is ...
Zhang Hainan +2 more
doaj
Remove-Win: a Design Framework for Conflict-free Replicated Data Collections
Internet-scale distributed systems often replicate data within and across data centers to provide low latency and high availability despite node and network failures.
Huang, Yu +3 more
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Web is an efficient way to disseminate all the data behind the conclusion given in a traditional journal documents which can provide to the user even complex data in a re-useable form but this is only useful if the data can be found and understood in context, with appropriate provenance, can be cited to a source with adequate version control and ...
openaire +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

