Results 111 to 120 of about 11,289,377 (286)

SED, a normalization free method for DNA microarray data analysis

open access: yesBMC Bioinformatics, 2004
Background Analysis of DNA microarray data usually begins with a normalization step where intensities of different arrays are adjusted to the same scale so that the intensity levels from different arrays can be compared with one other.
Huang Hui, Wang Huajun
doaj   +1 more source

MaxDIA enables library-based and library-free data-independent acquisition proteomics. [PDF]

open access: yesNat Biotechnol, 2021
Sinitcyn P   +17 more
europepmc   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Metagenomic data of free cyanide and thiocyanate degrading bacterial communities

open access: yesData in Brief, 2017
The data presented in this article contains the bacterial community structure of the free cyanide (CN-) and thiocyanate (SCN-) degrading organisms that were isolated from electroplating wastewater and synthetic SCN- containing wastewater.
Lukhanyo Mekuto   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

SEISGAMA: A Free C# Based Seismic Data Processing Software Platform

open access: yesInternational Journal of Geophysics, 2018
Seismic reflection is one of the most popular methods in geophysical prospecting. Nevertheless, obtaining high resolution and accurate results requires a sophisticated processing stage.
Theodosius Marwan Irnaka   +5 more
doaj   +1 more source

Data from quantitative label free proteomics analysis of rat spleen

open access: yesData in Brief, 2016
The dataset presented in this work has been obtained using a label-free quantitative proteomic analysis of rat spleen. A robust method for extraction of proteins from rat spleen tissue and LC-MS-MS analysis was developed using a urea and SDS-based buffer.
Khadar Dudekula, Thierry Le Bihan
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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