Results 91 to 100 of about 5,248,562 (283)
The computational anatomy of psychosis
Frontiers in Psychiatry, 2013 This paper considers psychotic symptoms in terms of false inferences or beliefs. It is based on the notion that the brain is an inference machine that actively constructs hypotheses to explain or predict its sensations.
Rick A Adams +6 more
doaj +1 more source
A Thermodynamic Formulation of Home Prices in a Monocentric City
Reports in Advances of Physical Sciences, 2020 In this work, we proposed a theoretical framework inspired by physical thermodynamics to explain the housing price distributions in monocentric cities. In the same spirit as the Alonso–Muth–Mills (AMM) model, we assume that the disposable income C=W−R(x)−
Peter Tsung-Wen Yen +2 more
doaj +1 more source
, 2008 Conventional quantum chemical solvation theories are based on the mean-field embedding approximation. That is, the electronic wavefunction is calculated in the presence of the mean field of the environment.
Yamamoto, Takeshi
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Shape dependent finite-size effect of critical two-dimensional Ising model on a triangular lattice
, 2012 Using the bond-propagation algorithm, we study the finite-size behavior of the critical two-dimensional Ising model on a finite triangular lattice with free boundaries in five shapes: triangle, rhombus, trapezoid, hexagon and rectangle. The critical free
Guo, Wenan +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Carbon Free Boston: Energy Technical Report [PDF]
, 2019 Part of a series of reports that includes: Carbon Free Boston: Summary Report; Carbon Free Boston: Social Equity Report; Carbon Free Boston: Technical Summary; Carbon Free Boston: Buildings Technical Report; Carbon Free Boston: Transportation ...
Cleveland, Cutler J. +4 more
core
, 2013 We derive some exact bounds on the free energy $W(J)$ in QCD, where $J_\mu^b$ is a source for the gluon field $A_\mu^b$ in the minimal Landau gauge, and $W(J)$ is the generating functional of connected gluon correlators. Among other results, we show that
Maas, Axel, Zwanziger, Daniel
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source