Results 61 to 70 of about 5,253,595 (284)

Surface free energy and microarray deposition technology [PDF]

open access: yes, 2007
Microarray techniques use a combinatorial approach to assess complex biochemical interactions. The fundamental goal is simultaneous, large-scale experimentation analogous to the automation achieved in the semiconductor industry.
Aussillous   +8 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Control of Overfitting with Physics

open access: yesEntropy
While there are many works on the applications of machine learning, not so many of them are trying to understand the theoretical justifications to explain their efficiency.
Sergei V. Kozyrev   +2 more
doaj   +1 more source

Escorted free energy simulations [PDF]

open access: yesThe Journal of Chemical Physics, 2011
We describe a strategy to improve the efficiency of free energy estimates by reducing dissipation in nonequilibrium Monte Carlo simulations. This strategy generalizes the targeted free energy perturbation approach [C. Jarzynski, Phys. Rev. E 65, 046122 (2002)] to nonequilibrium switching simulations, and involves generating artificial, “escorted ...
Vaikuntanathan, Suriyanarayanan   +1 more
openaire   +3 more sources

Magnetic free energy at elevated temperatures and hysteresis of magnetic particles

open access: yes, 2001
We derive a free energy for weakly anisotropic ferromagnets which is valid in the whole temperature range and interpolates between the micromagnetic energy at zero temperature and the Landau free energy near the Curie point T_c.
Brown   +15 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Study on the Magnetic-machine Coupling Characteristics of Giant Magnetostrictive Actuator Based on the Free Energy Hysteresis Characteristics

open access: yesSensors, 2018
A giant magnetostrictive actuator presents advantages such as large strain, high precision, and quick response. It is a hotly debated research topic in the field of micro drivers; however, the nonlinear intrinsic relationship between its output and input
Zhen Yu, Tao Wang, Min Zhou
doaj   +1 more source

Bubble Free Energy in Cosmological Phase Transitions

open access: yes, 1993
Free energy as a function of temperature and the bubble radius is determined for spherical bubbles created in cosmological first order phase transitions. The phase transition is assumed to be driven by an order parameter (e.g. a Higgs field) with quartic
Anderson   +16 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Capacitive Mixing for Harvesting the Free Energy of Solutions at Different Concentrations

open access: yesEntropy, 2013
An enormous dissipation of the order of 2 kJ/L takes place during the natural mixing process of fresh river water entering the salty sea. “Capacitive mixing” is a promising technique to efficiently harvest this energy in an environmentally clean and ...
Renéa van Roij   +5 more
doaj   +1 more source

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