Results 81 to 90 of about 5,248,562 (283)

Twist Free Energy in a Spin Glass

open access: yes, 2002
The field theory of a short range spin glass with Gaussian random interactions, is considered near the upper critical dimension six. In the glassy phase, replica symmetry breaking is accompanied with massless Goldstone modes, generated by the breaking of
Brézin, E., De Dominicis, C.
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Renormalized quark-anti-quark free energy

open access: yes, 2003
We present results on the renormalized quark-anti-quark free energy in SU(3) gauge theory at finite temperatures. We discuss results for the singlet, octet and colour averaged free energies and comment on thermal relations which allow to extract ...
Kaczmarek, O.   +3 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Structural analysis of CanOn-1S cluster of dolomite desulfurization

open access: yesMetalurgija, 2018
Using first-principles calculation method and comparing the difference between the free energy, the binding energy and electronic energy, the paper obtained CanOn-1S clusters is possible by the presence of CaO to CaS desulfurization process.
W. Z. Lv, K. Liu, R. W. Zhang, L. Cheng
doaj  

Rotation of Galaxies within Gravity of the Universe

open access: yesEntropy, 2016
Rotation of galaxies is examined by the general principle of least action. This law of nature describes a system in its surroundings, here specifically a galaxy in the surrounding Universe.
Arto Annila
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Brain activity and cognition: A connection from thermodynamics and information theory

open access: yesFrontiers in Psychology, 2015
The connection between brain and mind is an important scientific and philosophical question that we are still far from completely understanding. A crucial point to our work is noticing that thermodynamics provides a convenient framework to model brain ...
Guillem eCollell, Jordi eFauquet
doaj   +1 more source

Stability of Two-Dimensional Soft Quasicrystals

open access: yes, 2015
The relative stability of two-dimensional soft quasicrystals is examined using a recently developed projection method which provides a unified numerical framework to compute the free energy of periodic crystal and quasicrystals. Accurate free energies of
Jiang, Kai   +3 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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