Results 31 to 40 of about 1,552,141 (263)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Pengaruh Free Cash Flow terhadap Pertumbuhan Laba Perusahaan

open access: yesBenefit Jurnal Manajemen dan Bisnis, 2019
Free Cash Flow (FCF) merupakan sisa perhitungan arus kas yang tidak lagi digunakan untuk aktivitas operasi maupun investasi perusahaan. Penelitian ini bertujuan untuk menguji pengaruh FCF terhadap pertumbuhan laba perusahaan, di mana pada kondisi riil ...
Devi Erianti
doaj   +1 more source

Unsteady Flow Driven by the Counter-Flow Jets of High-Altitude Engine Based on DSMC Simulation

open access: yes气体物理, 2023
Counter-flow engines are often used for aircraft slowing or separating. In order to study the interaction between the counter-flow jets and free stream at high altitudes, the rarefied flow driven by two counter-flow jets and hypersonic free stream was ...
Jun-lin WU   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Shear-free boundary in Stokes flow

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1996
A theorem of Harper for axially symmetric flow past a sphere which is a stream surface, and is also shear-free, is extended to flow past a doubly-body 𝔅 consisting of two unequal, orthogonally intersecting spheres. Several illustrative examples are given.
D. Palaniappan   +2 more
doaj   +1 more source

Coefficient of Discharge for Free Flow Sluice Gates

open access: yesJournal of King Saud University: Engineering Sciences, 1999
This paper aims to investigate the effect of sill shape located under the sluice gate on the coefficient of discharge for free gate flow conditions. Both sill shape and sill height are studied. Shapes tested include both polygonal and non polygonal sills.
Abdualaziz A. Alhamid
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Corporate Governance And Relation between Free Cash Flow and Return [PDF]

open access: yesپژوهش‌های تجربی حسابداری, 2018
Conflict of interests usually occurs between management and shareholders on dividend and more severely in firms with significant free cash flow. If free cash flow is invested efficiently, stock return will be increase.
gholamreza kordestani   +2 more
doaj   +1 more source

Numerical simulation of flows around a finite-length cylinder with free surface

open access: yesZhongguo Jianchuan Yanjiu, 2022
ObjectivesIn order to explore the influence of the free surface and free end on the flow field around typical bluff bodies, the flow field around a finite-length cylinder with a free surface is studied. MethodsBased on the delay detached-eddy simulation (
Songtao CHEN   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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