Results 81 to 90 of about 688,287 (309)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

ROMANIAN SOCIAL MOVEMENT: BETWEEN REPOLITICIZATION AND REINFORCEMENT OF THE STATUS-QUO (2012-2017)

Studia Universitatis Babeş-Bolyai. Studia Europaea, 2017
The article states that the social movement that emerged in Romania in 2012 is part of the global anti-austerity movement. It proposes the movement’s analysis in the key of Karl Polanyi’s theory of double movement, portraying it as a counter-movement ...
Victoria STOICIU
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

National E-Systems for Combating VAT Evasion and Intra-EU Trade. Hungary’s ‘EAKER’ and Romania’s ‘RO e-Transport’

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(1), 55-96 | Article | (Table of Contents) 1. Introduction. – 2. A quick look at border and other types of checks. – 3. An overview of the two systems. – 3.1. Hungary’s EKAER.
Szilárd Gáspár-Szilágyi, Vasile Ianovici   +1 more
doaj   +1 more source

Trade in services of member states of the Eurasian Economic Union

RUDN Journal of Economics, 2019
The Treaty on the Eurasian Economic Union, which became effective since January 1, 2015, establishes the principles and the purposes of integration consolidation and also provides free movement of goods, services, the capital and labor power in the ...
Kuanysh N. Yelikbaev
doaj   +1 more source

Financial market integration in the EU: A practical inventory of benefits and hurdles in the Single Market [PDF]

, 2019
It is 25 years since the European Union (EU) agreed to complete the European Single Market (SM) in goods, ser- vices, people, and capital. While many barriers to the free movement of capital across borders have been removed, some important practical ...
Gnath, Katharina, Grosse-Rueschkamp, Benjamin, Kastrop, Christian, Ponattu , Dominic, Rocholl, Jörg, Wortmann, Marcus   +5 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Regionalizing Labor Policy Through NAFTA: Beyond President Bush’s Temporary Worker Proposal [PDF]

, 2005
The North American Free Trade Agreement (NAFTA) sought to create an expanded and secure market for the goods and services produced in its member territories.
Gunn, Elizabeth L
core