Dimeric Histidine as a Novel Free Radical Scavenger Alleviates Non-Alcoholic Liver Injury [PDF]
Non-alcoholic liver injury (NLI) is a common disease worldwide. Since free radical damage in the liver is a crucial initiator leading to diseases, scavenging excess free radicals has become an essential therapeutic strategy.
Zizhen Zhao+3 more
doaj +2 more sources
Phytochemical Study and Anti-inflammatory, Antidiabetic and Free Radical Scavenger Evaluations of Krameria pauciflora Methanol Extract [PDF]
The plant Krameria pauciflora MOC et. Sessé ex DC. is used as an anti-inflammatory and antidiabetic in traditional medicine. The aim of this study was to evaluate the in vivo anti-inflammatory and antidiabetic effects of a methanol extract from the roots
A. Berenice Aguilar-Guadarrama+3 more
doaj +4 more sources
Suppression of Inflammation-Associated Kidney Damage Post-Transplant Using the New PrC-210 Free Radical Scavenger in Rats [PDF]
Allograft kidney transplantation, which triggers host cellular- and antibody-mediated rejection of the kidney, is a major contributor to kidney damage during transplant.
Torsten R. Goesch+6 more
doaj +2 more sources
Habitat of in vivo transformation influences the levels of free radical scavengers in Clinostomum complanatum: implications for free radical scavenger based vaccines against trematode infections. [PDF]
BackgroundSince free radical scavengers of parasite origin like glutathione-S-transferase and superoxide dismutase are being explored as prospective vaccine targets, availability of these molecules within the parasite infecting different hosts as well as
Atif Zafar+3 more
doaj +2 more sources
Antinociceptive effect of phenyl N-tert-butylnitrone, a free radical scavenger, on the rat formalin test [PDF]
BackgroundReactive oxygen species (ROS) such as superoxide radicals, hydrogen peroxide, nitric oxide, and nitroperoxide, cause oxidative stress which interferes with normal cell functioning, resulting in cell damage.
Young Kwon Ko+7 more
doaj +2 more sources
Complex Compound with Transitional Metal of AkwayBark (Drimys piperitaHook F.) as Low Molecular Weight Scavenging Antioxidant: A Computational Study [PDF]
Akway(Drimys piperitaHook f.) was known as an endogenous plant of Indonesia. This plant was investigated as a free radical scavenger based on paramagnetic prop-erties.
Hostalige Hutasoit+3 more
doaj +1 more source
Captopril: a free radical scavenger. [PDF]
The use of captopril in heart failure and hypertension is becoming increasingly accepted. Captopril has a sulphydryl group in its molecular structure. We wondered if this might confer free radical scavenging activity on the drug and have investigated this in an in vitro system. Results show that captopril is a free radical scavenger and we suggest that
Chopra, M.+6 more
openaire +4 more sources
Scavenging Effects of Dexrazoxane on Free Radicals [PDF]
Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron, thus preventing iron-based oxygen radical formation ...
Zhao Yan, Zhao Baolu, Zhang Junjing
openaire +3 more sources
Free radical scavenging activity of propolis [PDF]
We investigated the radical scavenging activity of propolis by ESR spectroscopy using spin trapping method. In addition, we examined the influence of a diet of 2% propolis on mice under oxidative stress. At low concentrations, the methanolic extract of propolis exhibited strong scavenging activity in vitro towards both the superoxide anion radical ...
Kazutoyo Endo+7 more
openaire +2 more sources
Application of a free radical scavenger edaravone in patients with hemorrhagic stroke
BACKGROUND. The free radical scavenger edaravone helps to reduce the area of ischemic injury and improve the longterm effects of stroke, and is therefore widely used in the treatment of ischemic stroke.
O.A. Halushko
doaj +1 more source