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Free Radical Scavenging Activity of Carnosine
Free Radical Research Communications, 1991The capacity of carnosine to decrease free radical-induced damage was evaluated using the oxidation of brain homogenates, the 2,2'-azobis-2-amidino propane-induced oxidation of erythrocyte ghost membranes, the radiation induced inactivation of horseradish peroxidase and the 2,2'-azobis-2-amidino propane-induced inactivation of lysozyme.
M, Salim-Hanna, E, Lissi, L A, Videla
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Free radical‐scavenging properties of lignin
Nutrition and Cancer, 1998Lignin is one of the major components of dietary fiber. It is a complex hydrophobic molecule that typically occurs in cell walls with heteroxylans. Our experimental data show that lignin is a free radical scavenger. When the NADH-phenazine methosulfate-nitro blue tetrazolium free radical-producing system is used, an alkali-lignin concentration of 46.29
F J, Lu, L H, Chu, R J, Gau
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Gliclazide: a general free radical scavenger
European Journal of Pharmacology: Molecular Pharmacology, 1991Free radical mechanisms have been implicated in diabetic microangiopathy. Agents that scavenge free radicals may be beneficial. We assessed the scavenging ability of two sulphonylureas, gliclazide and glibenclamide, in vitro. The assay which employs o-dianisidine sensitised by riboflavin can be used to distinguish between superoxide scavengers and ...
Scott, Norma A. +3 more
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The anticonvulsant zonisamide scavenges free radicals
Epilepsy Research, 1998Zonisamide (ZNS) is effective in animal models of epilepsy and epileptic patients. The free radical scavenging activities of ZNS were analyzed by using electron spin resonance. ZNS, in the mmolar range, scavenged hydroxyl and nitric oxide radicals in a dose-dependent manner.
A, Mori, Y, Noda, L, Packer
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Free radical scavenging Activity :
DIU Journal of Health and Life Sciences, 2014The present study was aimed at investigating the chemical profiles of the methanolic extract of leaves of Centella asiatica as well as to assess its antioxidative activity. In this study, a methanolic extract (50 g/L) was obtained by infusion followed by cold maceration for 24 h.
Md. Mustafezur Rahman +4 more
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Free Radical Scavenging Properties of Sulfinpyrazone
Free Radical Research, 2002Sulfinpyrazone, a potent uricosuric drug, was tested in vitro for its scavenging action against oxygen free radicals. In this study, sulfinpyrazone was able to scavenge 1,1-diphenyl-2-picrylhydrazyl radical with IC50 value of 29.82 micrograms/ml compared to butylated hydroxytoluene (BHT, IC50 value = 20.15 micrograms/ml) and Trolox (IC50 value = 16.01 ...
Mei-Ling, Yang +3 more
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Allantoin as a Free-Radical Scavenger
Doklady Biochemistry and Biophysics, 2002In vertebrates, free purine bases are deaminated mainly to hypoxantine (Ia) or xantine (Ib), which are further oxidized to uric acid (Ic) in the presence of oxygen. Its further conversion (Ic to If) is shown in the following scheme:
E P, Gus'kov +7 more
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Free Radical Scavenging Action of Baicalein
Archives of Biochemistry and Biophysics, 1993TJ-960 is a Japanese Kampo (traditional herbal) medicine used for the treatment of epilepsy. It's a crude drug, an extract of nine herbs, and consists of many known and unknown components. Among the known components of TJ-960, we found that 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one (baicalein) might be the most potent scavenger for radicals.
H, Hamada +3 more
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Copper or free radical scavenger?
Computational and Theoretical Chemistry, 2017Abstract Free radicals are very reactive molecules that produce so-called oxidative stress. To prevent oxidative stress there are two types of molecules: primary and secondary antioxidants. The chelation of copper is an example of a secondary antioxidant process. Therefore, these secondary antioxidants can be named copper scavengers. The main purpose
Ana Martínez, Miguel Reina
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Modulation of platelet function by free radicals and free-radical scavengers
Trends in Pharmacological Sciences, 1993Platelets have the capacity to generate oxygen-derived free radicals and are often present at inflammatory foci with other free-radical-generating cells such as white blood cells. Free radicals can modify platelet adhesion and aggregation directly or through effects on the vascular endothelium, which generates prostacyclin and nitric oxide.
D, Salvemini, R, Botting
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