Results 41 to 50 of about 5,663,581 (403)

Free radicals, natural antioxidants, and their reaction mechanisms

, 2015
The normal biochemical reactions in our body, increased exposure to the environment, and higher levels of dietary xenobiotic's result in the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS). The ROS and RNS create oxidative
S. B. Nimse, D. Pal
semanticscholar   +1 more source

Free radicals and senescence [PDF]

Experimental Cell Research, 2008
There is a significant body of experimental evidence that a rise in intracellular reactive oxygen species (ROS) contributes to senescence. Here we review experiments where entry into senescence has been evaluated in cells whose intracellular ROS levels have been modulated by growth in either high or low ambient oxygen concentrations, or where the ...
Teng Lu, Toren Finkel
openaire   +3 more sources

Doppler-free laser spectroscopy of buffer gas cooled molecular radicals [PDF]

, 2009
We demonstrate Doppler-free saturated absorption spectroscopy of cold molecular radicals formed by laser ablation inside a cryogenic buffer gas cell. By lowering the temperature, congested regions of the spectrum can be simplified, and by using different
Hendricks, R. J., Hinds, E. A., Hudson, J. J., Sauer, B. E., Segal, D. M., Sinclair, C. D. J., Skoff, S. M., Tarbutt, M. R.   +7 more
core   +1 more source

Free Radicals, Antioxidants in Disease and Health

International Journal of Biomedical Science, 2008
Free radicals and oxidants play a dual role as both toxic and beneficial compounds, since they can be either harmful or helpful to the body. They are produced either from normal cell metabolisms in situ or from external sources (pollution, cigarette ...
Lien Ai Pham-Huy, Hua-Dong He, C. Pham-Huy   +2 more
semanticscholar   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

Population Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

Computational study of radicals derived from hydroxyurea and its methylated analogues. [PDF]

, 2012
Structural and electronic properties and chemical fate of free radicals generated from hydroxyurea (HU) and its methylated analogues N-methylhydroxyurea (NMHU) and O-methylhydroxyurea (OMHU) are of utmost importance for their biological and ...
Birus, Mladen, Sakic, Davor, Vinkovic Vrcek, Ivana, Vrcek, Valerije, Zipse, Hendrik   +4 more
core   +1 more source

Moving in the Dark: Enlightening the Spatial Population Ecology of European Cave Salamanders

Population Ecology, EarlyView.
We assessed individual interactions, movement ecology and activity patterns of a subterranean population of Speleomantes strinatii, applying spatial capture–recapture modeling to a photographic dataset of 104 individuals. ABSTRACT Space use and movement are fundamental aspects of organisms' ecology, mirroring individual fitness, behavior, and life ...
Giacomo Rosa, Andrea Costa, Sebastiano Salvidio   +2 more
wiley   +1 more source

Identification of Peroxiredoxin (PRX) Genes from Pepper Fruits: Involvement in Ripening and Modulation by Nitric Oxide (NO)

Antioxidants
Peroxiredoxins (Prxs; EC 1.11.1.15) are a group of thiol peroxidases that catalyze the detoxification of H2O2 and other organic hydroperoxides. The ripening of pepper (Capsicum annuum L.) fruit involves significant phenotypic, physiological, and ...
Fátima Ramírez-Mellado, Salvador González-Gordo, José M. Palma, Francisco J. Corpas   +3 more
doaj   +1 more source

A Bright, Slow Cryogenic Molecular Beam Source for Free Radicals

, 2011
We demonstrate and characterize a cryogenic buffer gas-cooled molecular beam source capable of producing bright beams of free radicals and refractory species.
Abuaf, Ahern, André, Balakrishnan, Ball, Barnett, Carr, D. DeMille, Davis, De Dea, Decarvalho, DeMille, DeMille, DeMille, Dietz, Dondi, Dun, E. S. Shuman, Elioff, Fernandez de La Mora, Flambaum, Fletcher, Fulton, Goral, Gupta, Hamel, Hillenkamp, Hogervorst, Hopkins, Hudson, Hudson, Hudson, Hutzler, J. F. Barry, Krems, Leanhardt, Lu, Maussang, Maxwell, Mazely, Micheli, Narevicius, Ni, Patterson, Patterson, Ramos, Reis, Sage, Sedgley, Sherman, Shuman, Shuman, Skoff, Strebel, Tarbutt, Tarbutt, Tejeda, Tobin, Toennies, Tsikata, Tu, van Buuren, van de Meerakker, Vanhaecke, Vutha, Wall, Wang, Weinstein   +67 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source