Results 61 to 70 of about 320,731 (312)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Persistent Free Radicals in Petroleum

open access: yes, 2023
The persistent free radical content in petroleum is of the order 1018 spins/g (1 μmol/g), with higher and lower values found depending on origin and in different distillation fractions.
Joy H. Tannous   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Oxygen Free Radicals in Shock

open access: yes, 1986
Experimental and clinical evidence of the role of osygen free radicals in myocardial ischemia and ...
CECONI, Claudio   +5 more
core  

The oxime portmanteau motif : released heteroradicals undergo incisive EPR interrogation and deliver diverse heterocycles

open access: yes, 2014
OA funded through the RCUK OA block grant.Selective syntheses are now available for compounds of many classes, based on C-centered radicals, exploiting a diverse range of mechanisms.
John C. Walton, Walton, John Christopher
core   +1 more source

radical (free radical)

open access: yes, 2014
Citation: 'radical (free radical)' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05066 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Plant peroxisomes: A nitro-oxidative cocktail

open access: yesRedox Biology, 2017
Although peroxisomes are very simple organelles, research on different species has provided us with an understanding of their importance in terms of cell viability.
Francisco J. Corpas   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Thioimidoyl Radicals as a Novel Tin-Free Source of Alkyl Radicals

open access: yes, 2004
The radical reaction of alkanethiols with tert-butyl isocyanide in boiling benzene gives rise to intermediate thioimidoyls radicals which undergo easy fragmentation yielding tert-butyl isothiocyanate and corresponding alkyl radicals.
ZANARDI, GIUSEPPE   +8 more
core  

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