Results 41 to 50 of about 1,645,533 (278)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

On the enumeration of closures and environments with an application to random generation [PDF]

open access: yesLogical Methods in Computer Science, 2019
Environments and closures are two of the main ingredients of evaluation in lambda-calculus. A closure is a pair consisting of a lambda-term and an environment, whereas an environment is a list of lambda-terms assigned to free variables.
Maciej Bendkowski, Pierre Lescanne
doaj   +1 more source

The norm of products of free random variables [PDF]

open access: yesProbability Theory and Related Fields, 2006
16 pages; forthcoming in Probability Theory and Related ...
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Automated sepsis prediction from unstructured electronic health records using natural language processing: a retrospective cohort study

open access: yesBMJ Health & Care Informatics
Objective Artificial intelligence (AI) holds promise for predicting sepsis. However, challenges remain in integrating AI, natural language processing (NLP) and free text data to enhance sepsis diagnosis at emergency department (ED) triage.
Matthew Anstey   +6 more
doaj   +1 more source

Development of a new Pro-rata warranty policy for estimating costs [PDF]

open access: yesمدیریت صنعتی, 2014
In today’s fiercely competitive products market, product warranty has started playing an important role. Currently, a large number of products are being sold with warranty policies in the form of free replacement warranty, pro-rata warranty, and combined
Mahdi Nasrollahi   +3 more
doaj   +1 more source

Performance Analysis of Adopting FSO Technology for Wireless Data Center Network

open access: yesSystems, 2023
Free Space Optical Communication (FSO) is a promising technology to address wired Data Center Network (DCN) challenges like power consumption, low scalability and flexibility, congestion and cabling.
Amer AlGhadhban   +3 more
doaj   +1 more source

Orbital approach to microstate free entropy

open access: yes, 2007
Motivated by Voiculescu's liberation theory, we introduce the orbital free entropy $\chi_orb$ for non-commutative self-adjoint random variables (also for "hyperfinite random multi-variables").
Biane Ph.   +7 more
core   +1 more source

Failure of the Raikov Theorem for Free Random Variables [PDF]

open access: yes, 2004
We show that the sum of two free random variables can have a free Poisson law without any of them having a free Poisson law.
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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