Results 61 to 70 of about 1,645,533 (278)

On the anti-commutator of two free random variables

open access: yesIndiana University Mathematics Journal, 2023
Let $(κ_n(a))_{n\geq 1}$ denote the sequence of free cumulants of a random variable $a$ in a non-commutative probability space $(\mathcal{A},φ)$. Based on some considerations on bipartite graphs, we provide a formula to compute the cumulants $(κ_n(ab+ba))_{n\geq 1}$ in terms of $(κ_n(a))_{n\geq 1}$ and $(κ_n(b))_{n\geq 1}$, where $a$ and $b$ are freely
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Symmetries, variational principles, and quantum dynamics

open access: yesDiscrete Dynamics in Nature and Society, 2004
We describe the role of symmetries in formation of quantum dynamics. A quantum version of d'Alembert's principle is proposed to take into account the symmetry constrains more exact.
J. Manjavidze, A. Sissakian
doaj   +1 more source

Some Identities Involving Derangement Polynomials and Numbers and Moments of Gamma Random Variables

open access: yesJournal of Function Spaces, 2020
The problem of counting derangements was initiated by Pierre Rémond de Montmort in 1708. A derangement is a permutation that has no fixed points, and the derangement number Dn is the number of fixed point free permutations on an n element set ...
Lee-Chae Jang   +3 more
doaj   +1 more source

A free central-limit theorem for dynamical systems

open access: yes, 2020
The free central-limit theorem, a fundamental theorem in free probability, states that empirical averages of freely independent random variables are asymptotically semi-circular.
Austern, Morgane
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A pseudo-analytic generalization of the memoryless property for continuous random variables and its use in pricing contingent claims

open access: yesRoyal Society Open Science
We explore an extension of the memoryless property for continuous random variables by using the concept of pseudo-sum. Subsequently, we demonstrate the practicality of this approach through two financial applications in which pseudo-sums characterize the
Peter Carr, Pasquale Cirillo
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models

open access: yesScientific Reports, 2023
Laryngeal squamous cell carcinoma (LSCC) is a common tumor type. High recurrence rates remain an important factor affecting the survival and quality of life of advanced LSCC patients.
Yi-Fan Zhang   +5 more
doaj   +1 more source

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