Results 141 to 150 of about 4,892,815 (298)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Revista Cubana de Investigaciones Biomédicas, 2010 Con el fin de estimular el uso de R en la investigación clínica y a partir de la experiencia con este software para el procesamiento y análisis de datos, se muestran algunas de sus características y las principales ventajas que ofrece su utilización en ...
MayelÍn Mirabal Sosa +2 more
doaj
SSD - a free software for designing multimeric mono-, bi- and trivalent shRNAs. [PDF]
Genet Mol Biol, 2020 Carli GJ +9 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Revista Fuentes El Reventón Energético, 2009 This paper shows the implementation of a neurosimulation technique for the well placement applied to the development of a heterogeneous hydrocarbon field with an irregular geometry.
Elkin Rodolfo Santafe Rangel +1 more
doaj
CroSSED sequence, a new tool for 3D processing in geosciences using the free software 3DSlicer. [PDF]
Sci Data, 2020 Dorador J, Rodríguez-Tovar FJ.
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Comparing Eight Parameter Estimation Methods for the Ratcliff Diffusion Model Using Free Software. [PDF]
Front Psychol, 2020 Alexandrowicz RW, Gula B.
europepmc +1 more source