Results 61 to 70 of about 991,958 (262)
Homogeneous isosceles-free spaces
Revista de la Real Academia de Ciencias Exactas, Físicas y Naturales. Serie A. MatemáticasAbstractWe study homogeneity aspects of metric spaces in which all triples of distinct points admit pairwise different distances; such spaces are called isosceles-free. In particular, we characterize all homogeneous isosceles-free spaces up to isometry as vector spaces over the two-element field, endowed with an injective norm.
Christian Bargetz +3 more
openaire +5 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Multimode Collective Atomic Recoil Lasing in Free Space
Atoms, 2020 Cold atomic clouds in collective atomic recoil lasing are usually confined by an optical cavity, which forces the light-scattering to befall in the mode fixed by the resonator.
Angel T. Gisbert, Nicola Piovella
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
New Journal of Physics, 2012 The statistical fluctuations in free-space links in the turbulent atmosphere are important for the distribution of quantum signals. To that end, we first study statistics generated by the turbulent atmosphere in an entanglement-based free-space quantum ...
C Erven +6 more
doaj +1 more source
Analysis of Free-Space Optics Development
Metrology and Measurement Systems, 2017 The article presents state of work in technology of free-space optical communications (Free Space Optics − FSO). Both commercially available optical data links and their further development are described.
Mikołajczyk Janusz +7 more
doaj +1 more source