Results 81 to 90 of about 1,020,372 (262)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Analysis of Free-Space Optics Development
Metrology and Measurement Systems, 2017 The article presents state of work in technology of free-space optical communications (Free Space Optics − FSO). Both commercially available optical data links and their further development are described.
Mikołajczyk Janusz +7 more
doaj +1 more source
SPACES OF FREE LOOPS ON REAL PROJECTIVE SPACES
Kyushu Journal of Mathematics, 2005 Let \(L(X)\) be the free loop space on \(X\). For \(X= S^m\) or \(\mathbb{R} P^m\) there is a natural decomposition \(L_0(X)\coprod L_1(X)\) and natural maps \(Q^{n,d}_0(X)\to L_0(X)\), \(Q^{n,d}_1(X)\to L_1(X)\) where \(Q^{n,d}_{\varepsilon}(X)\), \(\varepsilon= 0,\,1\) are defined in terms of \(n\)-tuples of polynomials with real or complex ...
openaire +3 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
New Journal of Physics, 2012 The statistical fluctuations in free-space links in the turbulent atmosphere are important for the distribution of quantum signals. To that end, we first study statistics generated by the turbulent atmosphere in an entanglement-based free-space quantum ...
C Erven +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Calibration methods for microwave free space measurements [PDF]
Advances in Radio Science, 2004 In this article calibration methods for the precise, contact-less measurement of the permittivity, permeability or humidity of materials are presented.
I. Rolfes, B. Schiek
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