Results 71 to 80 of about 991,958 (262)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Calibration methods for microwave free space measurements [PDF]

open access: yesAdvances in Radio Science, 2004
In this article calibration methods for the precise, contact-less measurement of the permittivity, permeability or humidity of materials are presented.
I. Rolfes, B. Schiek
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Dust-Free Spaces [PDF]

open access: yesNature, 1884
Mr. Serrell is no doubt perfectly correct in his view that the average specific gravity of a warmed and vapour-filled cloud may be often less than that of air. The ascent of the so-called “steam” from a kettle proves this, and he will find the view clearly stated in Maxwell's “Heat,” p. 280. I did not enter into details in the Dublin lecture, but I was
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A Dual-Circularly Polarized Antenna Array for Space Surveillance: From Design to Experimental Validation

open access: yesApplied Sciences
This paper presents the design, simulation, and experimental validation of a dual-Circularly Polarized (CP) array antenna to be used as single element for a bistatic radar system, aimed at detecting and tracking objects in Low Earth Orbit (LEO).
Chiara Scarselli   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

FREE QUASICONFORMALITY IN BANACH SPACES IV

open access: yesAnnales Academiae Scientiarum Fennicae Series A I Mathematica, 1990
[For part II see the review above.] In this part, I first give various characterizations for coarsely quasihyperbolic and freely quasiconformal maps. For example, a homeomorphism \(f:G\to G'\) is freely quasiconformal if and only if (1) there is \(M>0\) such that \[ d(f\bar B(x,r)) \leq Md(f\bar B(x,r),\partial fB(x,2r)), \] whenever the open ball \(B ...
openaire   +5 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Free space method using a vector network analyzer to determine the dielectric permittivity of materials in microwave range

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Modified free space method using a vector network analyzer is proposed. The algorithm for determining the dielectric constant is developed. The results of measurements of the amplitude and phase of the reflection coefficient and transmission coefficient ...
N. A. Pevneva   +2 more
doaj  

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