Results 61 to 70 of about 9,437,217 (301)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Steady free surface flows induced by a submerged ring source or sink [PDF]

, 2012
The steady axisymmetric flow induced by a ring sink (or source) submerged in an unbounded inviscid fluid is computed and the resulting deformation of the free surface is obtained.
Forbes, L.K., Forbes, Lawrence K., Hocking, G.C., Stokes, Tim E., Hocking, Graeme Charles, Stokes, T.E.   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigation of Keel Curvature Effect on the Hydrodynamic Characteristics of a V-Shaped Planing Surface

International Journal of Maritime Technology, 2015
In this paper, three-dimensional two phase turbulent free surface flow is solved by an in-house code. The incompressible Reynolds average Navier-Stocks equations (RANS) with k-ε turbulence model are solved by the finite volume method in the non ...
Hashem Moradi, Amir Hossein Nikseresht, Alireza Mostofizadeh   +2 more
doaj  

Review of the Near-Water Effect of Rotors in Cross-Media Vehicles

Drones
Cross-media vehicles, which combine the advantages of airplanes and submarines, are capable of performing complex tasks in different media and have attracted significant interest in recent years.
Xingzhi Bai, Mingqing Lu, Qi Zhan, Yu Wang, Daixian Zhang, Xiao Wang, Wenhua Wu   +6 more
doaj   +1 more source

A Micropump Driven by Marangoni Effect

Journal of Thermal Science and Technology, 2008
A micropump driven by the thermocapillary convection is proposed. The purpose of this study is to examine the flow structure in liquid region and the effect of the geometry on the performance of the present micropump. There are two significant advantages
Kenji SUGIMOTO, Kaoru IWAMOTO, Hiroshi KAWAMURA   +2 more
doaj   +1 more source

Hydrodynamic Forces of a Semi-Submerged Cylinder in an Oscillatory Flow

Applied Sciences, 2020
This work experimentally investigated the performance of hydrodynamic forces on a semi-submerged cylinder under an oscillatory flow. To generate the equivalent oscillatory flow, the semi-submerged cylinder is forced to oscillate in several combinations ...
Haojie Ren, Shixiao Fu, Chang Liu, Mengmeng Zhang, Yuwang Xu, Shi Deng   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Surface profile prediction and analysis applied to turning process [PDF]

, 2008
An approach for the prediction of surface profile in turning process using Radial Basis Function (RBF) neural networks is presented. The input parameters of the RBF networks are cutting speed, depth of cut and feed rate.
LU, Chen, COSTES, Jean-Philippe
core   +1 more source