Results 71 to 80 of about 9,437,217 (301)
Latin American Journal of Solids and StructuresA hierarchical finite element is developed for the free vibration analysis of a liquid in a rigid cylindrical tank with or without a free surface. It is a hierarchical quadrilateral element and has the advantage that the hierarchical mode number is ...
Sidi Mohammed Hamza Cherif +1 more
doaj +1 more source
Shui kexue jinzhan, 2020 This study investigates the hydrodynamic characteristics of a submerged horizontal circular cylinder under forced oscillation by using a 2-D two-phase flow numerical wave tank (NWT) model based on the viscous fluid theory.
Hongfei MAO +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Free surface flows : coalescence, spreading and dewetting [PDF]
, 2014 Capillary and wetting phenomena are an essential part of nature. Its presence is noticed in many circumstances where solid and liquid surfaces come into contact. In this thesis different types of capillary free surface flows are studied. The topics discussed are mainly the coalescence of viscous sessile drops, the Marangoni-spreading of locally ...
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Computer modelling of liquid sloshing in tanks under periodic loads
Вісник Харківського національного університету імені В.Н. Каразіна. Серія: Математичне моделювання, інформаційні технології, автоматизовані системи управлінняThe paper aims on developing the computer methodology for taking damping into account when analysing the stability of fluid movement in reservoirs and fuel tanks under periodic external loads Relevance.
Кирило Дегтярьов +4 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A rational approximation to the evolution of a free surface during fluid withdrawal through a point sink [PDF]
, 2010 The time varying flow in which fluid is withdrawn from a reservoir through a point sink of variable strength beneath a free surface is considered. Asymptotic techniques are used to derive an approximate solution to the flow that is valid at intermediate ...
Forbes, Lawrence K. +4 more
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