Results 81 to 90 of about 2,218 (160)

Inverse Correlation between Free Triiodothyronine to Free Thyroxine Ratio and Dietary Sodium Intake in Patients with Type 2 Diabetes Taking Dipeptidyl Peptidase 4 Inhibitors: A Retrospective Cohort Study

Clinical Diabetology
OBJECTIVE: This clinical study investigated the hypothesis that patients with type 2 diabetes, who consume more dietary sodium while taking dipeptidyl peptidase 4 inhibitors (DPP4is), would demonstrate increased iodothyronine deiodinase-2 activity ...
Shuichi Okada, Kazuya Okada, Junichi Okada, Koji Kikkawa, Eijiro Yamada, Tsugumichi Saito, Tetsuro Andou, Kihachi Ohshima   +7 more
doaj   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Thyroid Profile Among Type 2 Diabetes Mellitus: A Cross-Sectional Study in a Hospital in Goa

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Background: Diabetes mellitus has emerged as a significant public health issue globally, with India facing one of the highest diabetes prevalence rates.
Saiesh M. Mardolkar, Carlos N. Menezes, Abhishek Bicholkar, Ephraim Joe   +3 more
doaj   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

The Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet, Johannes Burtscher, Hannes Gatterer, Katharina Hüfner, Samuel Verges, Tadej Debevec, Martin Burtscher   +6 more
wiley   +1 more source

Letter to the editor: Association between thyroid dysfunction and cognitive impairment in type 2 diabetes mellitus: A cross‐sectional study

Journal of Diabetes Investigation, EarlyView.
Aysha Khalid, Meva Ram, Romaisa Khalid
wiley   +1 more source

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source