Results 91 to 100 of about 2,218 (160)

A Rare Overlap of AQP4 and MOG Seropositivity in Neuromyelitis Optica Spectrum Disorder: A Case Report

Clinical and Experimental Neuroimmunology, Volume 17, Issue 3, August 2026.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is an immune‐mediated disorder of the central nervous system associated with autoantibodies against aquaporin‐4 (AQP4). This is distinct from myelin‐oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), defined by anti‐MOG antibodies.
Sarah E. Butler, Siew Kar Chen, Mastura Monif   +2 more
wiley   +1 more source

The association between maternal FT3/FT4 ratio in early pregnancy and adverse neonatal outcomes: a retrospective cohort study

Frontiers in Endocrinology
IntroductionMaternal thyroid hormone homeostasis during early gestation is fundamental for fetal growth and development, yet the specific clinical implications of the ratio between free triiodothyronine and free thyroxine, a marker of peripheral ...
Xiaoyu Chen, Fuyu Yang, Fanlong Meng, Lixin Li, Zhongyang Han, Jiayue Wang, Qingliang Shao, Shuang Li, Wei Sun   +8 more
doaj   +1 more source

First Korean Case of 5q35.2q35.3 Microduplication With Reversed Sotos Syndrome Phenotype and Growth Hormone Deficiency: Expanding the Endocrine Spectrum

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1696-1701, July 2026.
ABSTRACT Sotos syndrome is an overgrowth disorder caused by nuclear receptor binding SET domain protein 1 (NSD1) haploinsufficiency, whereas reciprocal 5q35.2q35.3 microduplication produces a reversed phenotype with growth retardation, microcephaly, delayed bone age, and neurodevelopmental delay.
Sejin Kim, Jung Sook Ha, Jun Chul Byun
wiley   +1 more source

Taste and Smell Disturbances Associated With Secondary Adrenal Insufficiency: A Case Report

Journal of General and Family Medicine, Volume 27, Issue 4, July 2026.
ABSTRACT Background Adrenal insufficiency often presents with nonspecific symptoms, impeding early diagnosis. Taste and smell disturbances are rarely recognized as presenting features. Case Presentation We report the case of a 54‐year‐old man with a 3‐month history of persistent taste and smell disturbances accompanied by fatigue, loss of appetite ...
Takanori Izumi, Eri Doi, Yuki Tsutsui, Noboru Horinouchi, Rie Utsunomiya, Katsuhiko Yoshimura, Machiko Morita, Naoki Matsuda, Seiji Shiota   +8 more
wiley   +1 more source

FT4 Should Replace TSH in Diagnosing Abnormal Thyroid Function

McGill Journal of Medicine, 2020
In this paper, I argue that the method for diagnosing abnormal thyroid function should be the free serum thyroxine (FT4) test. The current and most widely used method for diagnosis is the thyroid stimulating hormone (TSH) test.
Kristen Marie Yaun, Ashley Kennedy
doaj  

A Phase II Trial of Perioperative Camrelizumab Plus Neoadjuvant Chemotherapy in Resectable Stage IIB–IIIB Lung Squamous Cell Carcinoma

MedComm, Volume 7, Issue 7, July 2026.
This phase II trial suggests the potential of perioperative camrelizumab plus neoadjuvant chemotherapy in patients with resectable stage IIB‐IIIB lung squamous cell carcinoma. The major pathological response rate (primary endpoint) was 60.0%, and the pathological complete response (pCR) rate was 44.4%.
Mingming Hu, Shuku Liu, Yi Han, Feng Wang, Yang Liu, Baohua Lu, Hongxia Li, Yuan Gao, Ying Wang, Wei Yang, Kang Shi, Bo Xiao, Qunhui Wang, Juan Du, Haifeng Lin, Xiaomi Li, Chong Wang, Tongmei Zhang   +17 more
wiley   +1 more source

Low‐normal birthweight in the first pregnancy as a risk factor for small for gestational age in the second pregnancy: A matched case–control study

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Background Recurrent obstetric complications may stem from chronic placental dysfunction or maternal vulnerability, with potential worsening across successive pregnancies. Subtle intrauterine growth restriction in a first pregnancy, even within the appropriate‐for‐gestational‐age (AGA) range, may signal underlying risk for subsequent adverse ...
Boujenah Jeremy, Beddock Richard, Patrick Rozenberg   +2 more
wiley   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Aging and Western Diet Synergistically Impair Hepatic Thyroid Hormone Signaling to Promote Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) in Mice

Aging Cell, Volume 25, Issue 7, July 2026.
Aging and Western diet synergistically impair hepatic thyroid hormone signaling through decreased Dio1 and increased Dio3 activity, depleting intrahepatic T4 and T3 in senescent hepatocytes. This thyroid hormone deficit drives inflammation, fibrosis, and accelerated MASLD progression.
Xinru Zhang, Madhulika Tripathi, Chun Ting Goh, Chee Seng Chan, Anita Boelen, Paul M. Yen, Brijesh Kumar Singh, Eveline Bruinstroop   +7 more
wiley   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, Volume 14, Issue 5, Page 1172-1182, July 2026.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source