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Levothyroxine Treatment During Pregnancy: A Metabolomics Study
ABSTRACT Levothyroxine is one of the most prescribed drugs during pregnancy. Our aim was to determine levothyroxine treatment‐associated changes in the metabolite profiles and link these to the health of the newborn. Metabolite profiles of 118 levothyroxine‐treated and 118 healthy control pregnancies were determined with nuclear magnetic resonance ...
Olli Kärkkäinen +3 more
wiley +1 more source
Free thyroxine index or effective thyroxine ratio?
The ability of the free thyroxine index (FTI) and the effective thyroxine ratio (ETR) to distinguish abnormal from normal thyroid function is compared in a series of 422 patients; they were equally successful in detecting hyperthyroidism. In hypothyroidism, however, the ETR values of 22% were within 95% 'normal' limits compared with 7,4% of the FTI ...
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Clinical Endocrinology, Volume 105, Issue 1, Page 122-125, July 2026.
Muhammad Muneeb Ibad +12 more
wiley +1 more source
Autoantibodies to thyroxin and interference with free-thyroxin assay.
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RAISED TOTAL THYROXINE AND FREE THYROXINE INDEX BUT NORMAL FREE THYROXINE
Lancet, The, 1979G Hennemann, E P Krenning, G Bos
exaly +2 more sources
A REAPPRAISAL OF THE FREE THYROXINE INDEX
Lancet, The, 1981The usefulness of the routine measurement of the free thyroxine index as opposed to that of total thyroxine only has been examined by analysis of 803 requests for thyroid function tests in adults. In only 2.7% of cases would a significantly different decision on the interpretation and the need for supplementary testing have been made by considering the
D J Goldie, S R Jones
exaly +3 more sources
Irish Journal of Medical Science, 1969
The direct estimation of serum thyroxine iodine (T4I) and the uptake of125I labelled thyroxine from serum by anion exchange resin (R.U.R.) can both be used independently to assess thyroid status. The results from these two tests can be combined to give a free thyroxine index (F.T.I.) which is believed to be proportional to the concentration of free ...
P P, Smyth, D K, O'Donovan
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The direct estimation of serum thyroxine iodine (T4I) and the uptake of125I labelled thyroxine from serum by anion exchange resin (R.U.R.) can both be used independently to assess thyroid status. The results from these two tests can be combined to give a free thyroxine index (F.T.I.) which is believed to be proportional to the concentration of free ...
P P, Smyth, D K, O'Donovan
openaire +2 more sources
JAMA: The Journal of the American Medical Association, 1975
THE CIRCULATING concentration of free thyroxine indicates, with rare exception, the physiologic status in regard to euthyroidism, hyperthyroidism, or hypothyroidism. Yet only a very small portion (about 0.05%) of the serum total thyroxine exists in this form. The remainder is bound to the thyroxine-binding proteins, notably thyroxine-binding globulin.
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THE CIRCULATING concentration of free thyroxine indicates, with rare exception, the physiologic status in regard to euthyroidism, hyperthyroidism, or hypothyroidism. Yet only a very small portion (about 0.05%) of the serum total thyroxine exists in this form. The remainder is bound to the thyroxine-binding proteins, notably thyroxine-binding globulin.
openaire +3 more sources

