Results 111 to 120 of about 13,293,810 (294)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Signboard, Installation, Roseland Free Public Library (Roseland, N.J.)

open access: yes, 1997
Photo of installation the signboard of the Roseland Free Public Library by five men who are holding the board and putting it in the grounds outside the ...

core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Gas Permeability through Polyimides: Unraveling the Influence of Free Volume, Intersegmental Distance and Glass Transition Temperature. [PDF]

open access: yesPolymers (Basel), 2023
Torres A   +11 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Flag of the Roseland Free Public Library (Roseland, N.J.)

open access: yes, 1997
Flag of the Roseland Free Public Library with the emblem of the three books and a red rose on top of them.

core  

Free Volume in Polymer Solids.

open access: yesKobunshi, 1994
高分子固体のアモルファス状態を記述するためには,微視的で動的な分布を含めた自由体積概念の正しい理解が不可欠である.本稿では,自由体積概念の歴史を気体,液体,高分子固体とたどり,巨視的な等自由体積理論を概括してから,最近急速に報告されはじめた微視的で動的な自由体積とその分布に関する情報をまとめてみた.
openaire   +2 more sources

Free volume in microcanonical multifragmentation

open access: yes, 1999
A modified version is in preparation.
Raduta, Al. H., Raduta, Ad. R.
openaire   +2 more sources

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