Results 131 to 140 of about 13,293,810 (294)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Characterization and Modeling of Free Volume and Ionic Conduction in Multiblock Copolymer Proton Exchange Membranes. [PDF]

Polymers (Basel), 2022
Gomaa MM, Sánchez-Ramos A, Ureña N, Pérez-Prior MT, Levenfeld B, García-Salaberri PA, Elsharkawy MRM.   +6 more
europepmc   +1 more source

Cake commemorating the 25th Anniversary of the Roseland Free Public Library (Roseland, N.J.)

, 1997
Photo of the cake commemorating the 25th Anniversary of the Roseland Free Public Library. It has red and green piping with the words, "Roseland Free Public Library and 25th Anniversary and an illustration of books in red.

core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Unravelling free volume in branched-cation ionic liquids based on silicon. [PDF]

Chem Sci, 2022
Bakis E, Goloviznina K, Vaz ICM, Sloboda D, Hazens D, Valkovska V, Klimenkovs I, Padua A, Costa Gomes M.   +8 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The Cation Effect on the Free Volume and the Solubility of H₂S and CO₂ in Ionic Liquids Based on Bis(2-Ethylhexyl) Sulfosuccinate Anion. [PDF]

Membranes (Basel), 2023
Sazanova TS, Akhmetshina AI, Petukhov AN, Vorotyntsev AV, Suvorov SS, Barysheva AV, Mechergui A, Nyuchev AV, Kazarina OV, Stepakova AN, Atlaskina ME, Atlaskin AA, Kryuchkov SS, Vorotyntsev IV.   +13 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Free Volume and Permeability of Mixed Matrix Membranes Made from a Terbutil-M-terphenyl Polyamide and a Porous Polymer Network. [PDF]

Polymers (Basel), 2022
Soto C, Carmona J, Freeman BD, Palacio L, González-Ortega A, Prádanos P, Lozano ÁE, Hernandez A.   +7 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source