Results 21 to 30 of about 336,297 (266)

Battle between plants as antioxidants with free radicals in human body [PDF]

open access: yesJournal of HerbMed Pharmacology, 2020
Free radicals are constructed by natural physiological activities in the human cells as well as in the environment. They may be produced as a result of diet, smoking, exercise, inflammation, exposure to sunlight, air pollutants, stress, alcohol and drugs.
Fatemeh Jamshidi-kia   +6 more
doaj   +1 more source

Efficient poisoning attacks and defenses for unlabeled data in DDoS prediction of intelligent transportation systems

open access: yesSecurity and Safety, 2022
Nowadays, large numbers of smart sensors (e.g., road-side cameras) which communicate with nearby base stations could launch distributed denial of services (DDoS) attack storms in intelligent transportation systems.
Li Zhong, Wu Xianke, Jiang Changjun
doaj   +1 more source

Evil and Free Will: Contemporary Free-Will Defense and Classical Theism

open access: yesPhilosophy. Journal of the Higher School of Economics, 2020
The article considers contemporary free will defences, proposed by A. Plantinga, R. Swinburne, according to which the existence of a world in which there is free will is something more valuable than the existence of a world in which there is no free will. It is shown that contemporary forms of free will defences share with atheistic arguments from evil
openaire   +2 more sources

Power and Nuclear Weapons: The Case of the European Union

open access: yesJournal for Peace and Nuclear Disarmament, 2020
For the European Union, nuclear weapons are a taboo. But the more the EU takes steps towards defense integration, the closer the moment comes that the role of the French nuclear weapons has to be discussed. This article hopes to clarify that debate.
Tom Sauer
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Plantinga and the Logical Problem of Evil [PDF]

open access: yesحکمت و فلسفه, 2007
The "logical problem of evil" is one kind of the "problem of evil." It is claimed that there is a logical inconsistency between belief in the existence of an omniscient, omnipotent, and wholly good God and belief in the existence of evil. Alvin Plantinga
hasan miandari
doaj   +1 more source

How Did Evil Come into the World? A Primordial Free-Will Theodicy

open access: yesReligions, 2023
James P. Sterba has provided a compelling argument to the effect that given the extent of significant, and indeed even horrendous, evil that an all-good and all-powerful being could have prevented, there is no God.
Mark Johnston
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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