Results 31 to 40 of about 336,297 (266)

Bridging the Mackie–Plantinga Debate on Evil with Ibn Arabi’s Metaphysics

open access: yesReligions
This study examines how Ibn Arabi’s metaphysics can address key challenges in the contemporary philosophical debate on the problem of evil. John Mackie famously argues that the existence of an omnibenevolent and omnipotent God is logically incompatible ...
Elif Nur Balci
doaj   +1 more source

Electronic cigarette liquid increases inflammation and virus infection in primary human airway epithelial cells. [PDF]

open access: yesPLoS ONE, 2014
The use of electronic cigarettes (e-cigarettes) is rapidly increasing in the United States, especially among young people since e-cigarettes have been perceived as a safer alternative to conventional tobacco cigarettes.
Qun Wu   +3 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

THE FREE WILL DEFENSE REVISITED: THE INSTRUMENTAL VALUE OF SIGNIFICANT FREE WILL

open access: yesInternational Journal of Theology, Philosophy and Science, 2019
Alvin Plantinga has famously responded to the logical problem of evil by appealing to the intrinsic value of significant free will. A problem, however, arises because traditional theists believe that both God and the redeemed who go to heaven cannot do wrong acts. This entails that both God and the redeemed in heaven lack significant freedom.
Frederick CHOO, Esther GOH
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Spinoza on Free Speech

open access: yesCzasopismo Prawno-Historyczne, 2017
Baruch Spinoza (1632-1677) was arguably the fi rst modern liberalist. His Theologico-Political Treatise (henceforward, “TPT”, followed by chapter number), which contains among other things a principled defense of free speech, was published anonymously in ...
Seppo Sajama
doaj   +1 more source

Compatibilism and the Free Will Defense

open access: yesFaith and Philosophy, 2013
The free will defense is a theistic strategy for rejecting a certain argument for the non-existence of God. The argument, sometimes called the “logical problem of evil,” insists that it is logically impossible for an omnipotent, omniscient, perfectly benevolent God to co-exist with evil. Since evil clearly exists, the argument goes, God does not.
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The relation Ship between mental rhythmic Sycle and defending filed of free player in volleyball. [PDF]

open access: yesمجلة الرافدين للعلوم الرياضية, 2008
Important of the study: The great concern in this study was to identify the relation ship between mental rhythmic sycle of which concentrating attention with defending on field of free player.
Azad .H. Qader
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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