Results 91 to 100 of about 25,607 (285)
Effective base point freeness [PDF]
Let \(X\) be a projective variety with ``good'' \(K_X\) and \(L\in\text{Pic}(X)\). It is very important to know when \(K_X+mL\) is base point free or very ample. Here the author uses a technique due to Ein and Lazarsfeld to extend Ein-Lazarsfeld's theorems to singular 3-folds and prove the following result: Theorem.
openaire +3 more sources
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Strongly Sublinear Algorithms for Testing Pattern Freeness [PDF]
For a permutation $\pi:[k] \to [k]$, a function $f:[n] \to \mathbb{R}$ contains a $\pi$-appearance if there exists $1 \leq i_1 < i_2 < \dots < i_k \leq n$ such that for all $s,t \in [k]$, $f(i_s) < f(i_t)$ if and only if $\pi(s) < \pi(t)$.
Ilan Newman, Nithin Varma
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Malaysian cultivated kenaf has been identified as a suitable raw material for linerboard production. This study examines the soda-antraquinone (soda-AQ) pulp of kenaf fibers versus old corrugated container (OCC) and unbleached softwood kraft pulps as the
Ahmad Azizi Mossello +6 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The groupoid attached to the action of PSL(2,Z) on the irrational reals by linear fractional transformations is free.
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Inductive Freeness of Ziegler’s Canonical Multiderivations
Abstract Let $${{\mathscr {A}}}$$ A be a free hyperplane arrangement. In 1989, Ziegler showed that the restriction $${{\mathscr {A}}}''$$
Torsten Hoge, Gerhard Röhrle
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