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Fundamentals of Freeze-Drying

2002
Given the increasing importance of reducing development time for new pharmaceutical products, formulation and process development scientists must continually look for ways to "work smarter, not harder." Within the product development arena, this means reducing the amount of trial and error empiricism in arriving at a formulation and identification of ...
Steven L, Nail   +3 more
openaire   +2 more sources

The Principles of Freeze-Drying

2014
This chapter provides an up-to-date overview of freeze-drying (lyophilization) with particular relevance to stabilizing live cells or viruses for industrial applications as vaccines or seed culture. The chapter discusses the importance of formulation, cycle development, validation, and the need to satisfy pharmaceutical regulatory requirements ...
Gerald D J, Adams   +2 more
openaire   +2 more sources

Freezing and Freeze-Drying of Bull Spermatozoa

American Journal of Physiology-Legacy Content, 1957
The possible dependance of survival upon the time spermatozoa are in contact with the protective substance glycerol, prior to exposure to low temperatures, was investigated. Pretreatment for 5 minutes provided at least as much protection as 18 hours.
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The Principles of Freeze-Drying

2007
This chapter provides an up-to-date overview of freeze-drying (lyophilization) with particulars relevance to stabilizing live cells or viruses for industrial applications as vaccines or seed culture. The chapter discusses the importance of formulation, cycle development, validation, and the need to satisfy pharmaceutical regulatory requirements ...
openaire   +2 more sources

Freeze Drying of Pharmaceuticals

2013
Freeze-drying is a key step in many pharmaceutical manufacturing processes, as it provides long-term stability to formulations containing an active pharmaceutical ingredient. This entry first addresses the problem of formulations and various phases of a freeze-drying process, namely freezing, primary and secondary drying.
openaire   +2 more sources

Canning, Freezing, and Freeze-Drying

1991
Rice (Oryza sativa) is a staple grain consumed by more than half of the world’s population (Hogan 1977). It is the chief source of calories in Asia and has become more popular in Western countries in recent years (Burns and Gerdes 1985). Common objections to using rice in Western countries include difficulty and length of preparation and established ...
openaire   +1 more source

Freeze Drying and Microwave Freeze Drying as Encapsulation Methods

2017
Encapsulation is used to protect sensitive materials from adverse environmental conditions and control their release during transportation, storage, and consumption. It is applied in various industrial sectors, such as food, nutraceutical, and pharmaceutical industries.
openaire   +1 more source

Freezing and freeze-drying of viruses

Cryobiology, 1967
W A, Rightsel, D, Greiff
openaire   +2 more sources

Optimization of the different phases of the freeze-drying process of solid lipid nanoparticles using experimental designs

International Journal of Pharmaceutics, 2023
Kimberley Elbrink   +2 more
exaly  

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