Results 11 to 20 of about 172,563,589 (112)

Early and Progressive Spinal Cord Atrophy in Spinocerebellar Ataxia Type 1. [PDF]

Mov Disord
Abstract Background Spinocerebellar ataxia type 1 (SCA1) is a rare, autosomal dominant neurodegenerative disorder characterized by progressive cerebellar and brainstem degeneration. Previous studies have shown that spinal cord atrophy is also a key aspect of SCA1 neuropathology.
Reniers CJM, van Prooije TH, Kapteijns KCJ, van Asten JJA, Mariotti C, Sarro L, Nigri A, Grisoli M, Coarelli G, Durr A, Scheenen T, van de Warrenburg B.   +11 more
europepmc   +2 more sources

5th Asian Oceanian Congress of Neuropathology along with the 5th Annual Conference of the Neuropathology Society of India - Meeting Abstracts, September 24–26, 2021

, 2022
The 5th Asian Oceanian Congress of Neuropathology along with the 5 th Annual Conference of the Neuropathology Society of India  (AOCN-NPSICON) was held in virtual mode on September 24–26, 2021, at National Institute of Mental Health and Neurosciences ...
Neuropathology Society of India
core   +1 more source

6th Annual Conference of the Neuropathology Society of India (NPSICON) - Meeting Abstracts, February 23–25, 2023

, 2023
The 6th Annual conference of the Neuropathology Society of India, (NPSICON 2023) was held in a virtual mode, from 23rd to 25th February 2023, hosted by the Division of Neuropathology, Department of Pathology, Christian Medical College ...
Neuropathology Society of India
core   +1 more source

A lifespan staging model of basal forebrain cholinergic vulnerability. [PDF]

Alzheimers Dement
Abstract The cholinergic neurons of the basal forebrain are among the most vulnerable cell types to age‐ and Alzheimer's disease‐related dysfunction and neurodegeneration. However, the biological bases of basal forebrain cholinergic vulnerability (the why) and the temporal sequence (the how) have yet to be fully resolved.
Shanks HRC, Chen S, Onuska KM, Schmitz TW.   +3 more
europepmc   +2 more sources

“Proven patriots”: the French diplomatic corps, 1789-1799 [PDF]

, 2011
This study analyzes a hitherto unexamined group, the French diplomatic corps during the Revolution (1789 to 1799), and focuses on the question of loyalty and conscience.
Frey, Linda S., Frey, Marsha L.
core   +2 more sources

How and why I fell into neuropathology [PDF]

, 2023
I\u27m going to explain how and why I fell into the Department of Neuropathology at the Pitié-Salpêtrière Hospital of Paris. I\u27d also like to sketch the history of French neuropathology in the years 1960-2010, as seen by a naive young student, and ...
Hauw, Jean-Jacques
core   +1 more source

High‐Fat Diet Exacerbates Neuropathology in a Transgenic Mouse Model of Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a rare and devastating neurodegenerative disorder. Accumulating clinical and preclinical evidence suggests that diabetes and insulin resistance may adversely influence MSA pathophysiology. Objective We investigated the potential association between diabetes, impaired glucose homeostasis, and MSA ...
Marie‐Laure Arotcarena, Anna Delamarre, Miguel Lopez‐Cuina, Hugo Martin, Elio Balpe, Xavier Fioramonti, Erwan Bezard, Wassilios G. Meissner   +7 more
wiley   +1 more source

Lewy bodies are surrounded by granulovacuolar degeneration bodies in dementia with Lewy bodies

Brain Pathology, EarlyView.
Here, we report Lewy bodies (LBs) to be enriched for tau‐laden granulovacuolar degeneration bodies (GVBs), suggesting a potential mechanistic interface between α‐synuclein and tau pathology in dementia with Lewy bodies (DLB). Abstract Lewy bodies (LBs), composed primarily of aggregated α‐synuclein (α‐syn), are the pathological hallmark of Lewy body ...
Searlait Thom, Pawel Palmowski, Andrew Porter, Joe O'Neill, Johannes Attems, Laura A. Smith, Viktor I. Korolchuk, Daniel Erskine   +7 more
wiley   +1 more source

Interlaboratory performance testing on EPIC v2.0 CNS tumor profiling demonstrates high reproducibility of tumor classification but reveals the need for harmonized copy number variation reporting

Brain Pathology, EarlyView.
Using the Infinium MethylationEPIC v2.0 array and Heidelberg Brain Tumor Classifier v12.8, 24 international laboratories achieved highly reproducible CNS tumor classification (97.9% correct; median β‐correlation r = 0.99), while copy number variation interpretation showed substantial interlaboratory variability, highlighting the need for harmonized CNV
Katrin Mauch‐Mücke, Christin Siewert, Lora Dimitrova, Sandra Pohl, Brendan Osberg, Annika K. Wefers, Julia Lorenz, Tanja Rothhammer‐Hampl, Till Acker, Alonso Barrantes‐Freer, Jean Boutonnat, Bérengère Dadone‐Montaudié, Claire Delbridge, Wolfgang Dietmaier, Sebastian Dintner, Hildegard Dohmen, Matthias Dottermusch, Daniel Erny, Katrin B. M. Frauenknecht, Tobias Goschzik, Patrick N. Harter, Daniela Hirsch, Yanghao Hou, Theo F. J. Kraus, Maggie Lee, Friederike Liesche‐Starnecker, Anne Mc Leer, Linea Melchior, Michael Mittelbronn, Wolf C. Müller, Shalima S. Nair, Julia E. Neumann, Pitt Niehusmann, Nicole Pfarr, Torsten Pietsch, Marco Prinz, Markus Rechsteiner, Regina Reimann, Laveniya Satgunaseelan, Veronica Skarpeteig, Anne J. Skjulsvik, Karl Sotlar, Isabelle Vanden Bempt, Erik Vassella, Katharina J. Weber, Gabriel Wasinger, Andreas Waha, Karen Zwaenepoel, Felix Sahm, Markus J. Riemenschneider, David Capper   +50 more
wiley   +1 more source

A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract Subjective cognitive decline (SCD) refers to cognitive concerns that may occur with or without objective impairment on standardized testing. Studies suggest that SCD may be an early clinical marker of Alzheimer's disease and related dementias, and that it can predict future objective cognitive decline and progression to dementia.
Mark A. Dubbelman, Tanisha G. Hill‐Jarrett, Silvia Chapman, Gustavo Alves Andrade dos Santos, Martina Azar, Ganesh M. Babulal, Tyler R. Bell, Mark A. Bernard, Carolina Boza‐Calvo, Anthony Q. Briggs, Omonigho Michael Bubu, Heather E. Cuevas, N. Maritza Dowling, Darlingtina K. Esiaka, Bernadette A. Fausto, Fabricio Ferreira de Oliveira, Carol E. Franz, Joyla A. Furlano, Christopher Gonzalez‐Corona, M. Aaron Guest, Veer Bala Gupta, Vivek K. Gupta, Daija Jackson, Jillian L. Joyce, Michael R. Kann, William S. Kremen, Athene Lee, Jairo E. Martinez, Arjun V. Masurkar, Maia A. McLin, Elisa de Paula França Resende, Zahra Rahemi, Brianca C. Renfro, Márlon Juliano Romero Aliberti, Shaina Shagalow, Andrea Slachevsky, Juliana N. De Souza Talarico, Jean François Trani, Carol Van Hulle, Leah Waltrip, Stephen Ojiambo Wandera, Charles C. Windon, Mônica Sanches Yassuda, Davide V. Moretti, Elizabeth Kuhn, Elke Butterbrod, Katherine A. Gifford, Sietske A. M. Sikkes, Raphael M. Castilhos, Rachel Nosheny, Shana D. Stites, a collaboration of the Alzheimer's Association International Society to Advance Alzheimer's Research and Therapy Subjective Cognitive Decline and Diversity and Disparities Professional Interest Areas   +51 more
wiley   +1 more source