Results 91 to 100 of about 6,346,538 (309)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

FREQUENCY MODULATION APPROACH BASED ON SPLIT-RING RESONATOR LOADED BY VARACTOR DIODE

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2020
In the paper, an approach to frequency modulation is presented using a split-ring resonator (SRR) loaded by a varactor diode. The modulation occurs due to the continuous time variation of capacitance of the varactor diode via changing of its bias voltage
Dmytro Vovchuk, Serhii Haliuk, Pavlo Robulets, Leonid Politanskyi   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Forward masking of frequency modulation [PDF]

The Journal of the Acoustical Society of America, 2012
Forward masking of sinusoidal frequency modulation (FM) was measured with three types of maskers: FM, amplitude modulation (AM), and a masker created by combining the magnitude spectrum of an FM tone with random component phases. For the signal FM rates used (5, 20, and 40 Hz), an FM masker raised detection thresholds in terms of frequency deviation by
Andrew J, Byrne, Magdalena, Wojtczak, Neal F, Viemeister   +2 more
openaire   +2 more sources

Frequency modulation of a series resonant dual active bridge to minimize the circulating reactive currents in the high frequency link

, 2016
A frequency modulation scheme is proposed for a Capacitor-Inductor-Inductor-Capacitor (CLLC) Resonant Dual Active Bridge (RDAB) that relies on dynamic retuning of the resonant capacitors to the switching frequency as it is modulated.
Vilathgamuwa, D. Mahinda, Malan, Wynand L., D. Mahinda Vilathgamuwa, Broadmeadow, Mark A.H., Mark A. H. Broadmeadow, Geoffrey R. Walker, Walker, Geoffrey R., Wynand L. Malan   +7 more
core   +1 more source

Frequency Regulation Adaptive Control Strategy of Wind Energy Storage System for Wind Speed Uncertainty

Energies
In order to reduce the negative influence of wind speed randomness and prediction error on frequency modulation, the reliability of the wind storage system was assessed effectively. In the wind storage frequency modulation system, a state of charge (SOC)
Changqing Chen, Lixiong Li
doaj   +1 more source

Simulation and measurement of frequency modulation insubmillimeter-wave gyrotron

, 1999
Frequency modulation of the gyrotron output has been numerically simulated employing the approximation of weakly relativistic, mono-velocity electron beam as well as a quasi-empirical approach. The simulation results are compared to a first experiment in
OGAWA, Isamu, YOSHIDA, Kiyohiko, NISHIDA, Naoki, IDEHARA, Toshitaka, Pereyaslavets, Michael   +4 more
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Cell modeling using frequency modulation.

PLoS ONE
Computational models of the cell can be used to study the impact of drugs and assess pathological risks. Typically, these models are computationally demanding or challenging to implement in dedicated hardware for real-time emulation.
Jerry Jacob, Nitish Patel, Sucheta Sehgal   +2 more
doaj   +1 more source