Results 121 to 130 of about 1,160,559 (367)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Wideband frequency modulation of frequency synthesisers

Electronics Letters, 1979
Two-point frequency modulation gives a flat frequency response irrespective of the loop cutoff frequency of a p.l.l. digital frequency synthesiser. The spurious modulation components otherwise generated are also then suppressed. The modulation index is typically limited to Nπ where N is the divider ratio.
Michael James Underhill, R. I. H. Scott
openaire   +2 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Frequency Modulation of Spin-Transfer Oscillators

, 2004
Spin-polarized dc electric current flowing into a magnetic layer can induce precession of the magnetization at a frequency that depends on current.
Kaka, S., Pufall, M. R., Rippard, W. H., Russek, S. E., Silva, T. J.   +4 more
core   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Temporal Modulation of the Control Parameter in Electroconvection in the Nematic Liquid Crystal I52

, 2000
I report on the effects of a periodic modulation of the control parameter on electroconvection in the nematic liquid crystal I52. Without modulation, the primary bifurcation from the uniform state is a direct transition to a state of spatiotemporal chaos.
D. Walgraef, E. Bodenschatz, G. Ahlers, G. Ahlers, H. Riecke, H. Riecke, I. Rehberg, I. Rehberg, J.P. Gollub, J.P. Gollub, J.P. Gollub, K. T. Alligood, L. Kramer, L. Kramer, M. de la Torre Juáurez, M. Dennin, M. Dennin, M. Treiber, M. Treiber, M.C. Cross, Michael Dennin, S. Fauve, S. Kai, S. Rasenat, U. Finkenzeller   +24 more
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

New Electromagnetic Modes in Space-Time Modulated Dispersion-Engineered Media

, 2017
We report on new electromagnetic modes in space-time modulated dispersion-engineered media. These modes exhibit unusual dispersion relation, field profile and scattering properties.
Caloz, Christophe, Chamanara, Nima, Deck-Léger, Zoé-Lise, Kalluri, Dikshitulu   +3 more
core   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Modulation efficiency of LiNbO₃ waveguide electro-optic intensity modulator operating at high microwave frequency

, 2009
The modulation efficiency, at high-frequency microwave modulation, of a LiNbO3 waveguide electro-optic modulator is shown to be degraded severely, especially when it is used as a frequency translator in a Brillouin-distributed fiber-sensing system.
Liao, Y., Meng, Z., Zhou, H.
core   +1 more source