Results 101 to 110 of about 11,992,356 (248)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Support Frequency

open access: yes, 2018
This files contains participant averages of the frequency of the support phase (single or double limb support) at the instance of ...
Gordon, Keith Edward   +1 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Finometer can function as a standalone instrument in blood pressure variability studies and does not require support equipment to determine breathing frequency

open access: yes, 2010
Objective: The Finometer (FMS, Finapres Measurement Systems, Amsterdam) records the beat-to-beat finger pulse contour and has been recommended for research studies assessing shortterm changes of blood pressure and its variability. Variability measured in
Towell, A.   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Child Support Program in Oregon

open access: yes, 2012
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.OrDocs shipping list 2014-16Title from cover"Revised ...

core  

An AC and DC Inertia Enhancement Strategy for Bidirectional Grid-Connected Converter in DC Microgrid

open access: yesEnergies
The virtual synchronous generator (VSG) strategy has good application prospects as an effective measure to improve the grid inertia level. However, VSG strategy cannot stabilize DC voltage and may even affect the stability of DC voltage.
Haiguo Tang   +4 more
doaj   +1 more source

Other title: For custodial parents, answers to common questions; Other title: Answers to common questions

open access: yes, 2017
Rev. 8/17.; Title from cover; Previously published: For custodial parent : answers to common questions / Support Enforcement Services. [Hartford, Connecticut] : State of Connecticut Judicial Branch, [2014].; "JDP-FM-196.
Connecticut. Judicial Branch. Support Enforcement Services Unit,
core   +1 more source

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