Results 51 to 60 of about 2,899,624 (297)
Fresh or frozen? Classifying ‘spare' embryos for donation to human embryonic stem cell research [PDF]
, 2010 This article is available open access, funded by the Wellcome Trust. It is distributed under a Creative Commons License (http://creativecommons.org/licenses/by/3.0/). Copyright @ 2010 Elsevier Ltd.United Kingdom (UK) funding to build human embryonic stem
Williams, C +11 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Journal of International Medical ResearchObjective This study aimed to compare the pregnancy outcomes of Day 2 (D2) fresh embryo transfer and D3 fresh embryo transfer in women with only one zygote with two pronuclei (2PN).
Yaping Ye +5 more
doaj +1 more source
Reproductive Medicine and Biology, 2019 Purpose To demonstrate the benefits of the freeze‐all strategy for in vitro fertilization treatment based on retrospective analyses. Methods Post‐thaw embryo survival rates of slow‐frozen embryos in 294 cycles and vitrified embryos in 12 195 cycles were ...
Yoshimasa Asada +5 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Comparative study of pregnancy outcomes and success rates in fresh and frozen embryo transfer cycles [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i ĪrānIntroduction: Today, although the knowledge about the success rate of assisted reproductive technologies has increased dramatically, but a detailed comparison regarding whether embryo freezing improves the outcomes of embryo transfer cycles has not been ...
Negin Rezavand +5 more
doaj +1 more source
Reproductive and Developmental Medicine, 2020 Objective: Vitrification prevents ice formation within the high concentration of cryoprotectant agents and allows the cells and extracellular milieu to solidify into a glass-like state.
Cai-Hong Li +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
International Journal of Reproductive BioMedicine, 2022 Background: Embryo quality may affect birth weight among neonates born through assisted reproductive technology. There are very limited studies assessing the adverse effect of transferring a poor-quality embryo with a good-quality one on neonatal ...
Saeideh Dashti +3 more
doaj +1 more source