Results 101 to 110 of about 42,151 (297)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Meat Freshness Prediction [PDF]
, 2023 In most retail stores, the number of days since initial processing is used as a proxy for estimating the freshness of perishable foods or freshness is assessed manually by an employee.
Casanova, Nathan +4 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Poor Man's Social Network: Consistently Trade Freshness For Scalability
, 2012 Typical social networking functionalities such as feed following are known to be hard to scale. Different from the popular approach that sacrifices consistency for scalability, in this paper we describe, implement, and evaluate a method that can ...
Liu, Jinyang +4 more
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Effect of Different Egg Box Brands and Types on Egg Weight Loss during Storage
ISPEC Journal of Agricultural SciencesEgg weight loss during storage is driven mainly by the loss of water and carbon dioxide through the eggshell pores and is an essential measure of freshness and commercial value. Moulded-pulp egg boxes form the immediate microenvironment around the eggs,
Ayşin KAHRAMAN AVCI +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
FoodsDetermining the oxygen barrier packaging material is crucial for maintaining the quality and freshness of chilled chicken during low-temperature storage.
Debao Wang +7 more
doaj +1 more source
Analytical methods for estimation freshness of fish [PDF]
, 1978 It needs hardly be stressed that freshness is one of the essential factors of fisheries products. The quality of fresh fish as well as that of processed fisheries products depends upon the freshness of fish when it is landed at the port, delivered to ...
Uchiyama, Hitoshi
core
Protecting the flavors : freshness as a key to quality
, 2017 Since the early days of the specialty coffee movement, freshness has been one of its central pillars. Freshness is best defined as having original unimpaired qualities.
Wyser, Yves +5 more
core +1 more source