Results 31 to 40 of about 506,862 (302)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Experimental study of solar air heater with C-shaped ribs coated with zeolite [PDF]

Chemical Industry and Chemical Engineering Quarterly
A study was conducted to determine the heat transmission rate and friction properties of a solar air heater's (SAH) absorber by including a c-shaped rib, with and without perforations, and the efficiency of this absorber with and without zeolite coating ...
Petchimuthu Sureshkumar, Rajendran Sathiya Moorthy   +1 more
doaj   +1 more source

One-log call iterative solution of the Colebrook equation for flow friction based on Pade polynomials [PDF]

, 2018
The 80 year-old empirical Colebrook function zeta, widely used as an informal standard for hydraulic resistance, relates implicitly the unknown flow friction factor lambda, with the known Reynolds number Re and the known relative roughness of a pipe ...
Brkić, Dejan, Praks, Pavel
core   +5 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Estimating friction factors while drilling [PDF]

Journal of Petroleum Science and Engineering, 2019
Abstract We design and test an algorithm for estimating the bit angular velocity and side forces on a drill string using only topside measurements fed into an adaptive observer. To derive the algorithm gains the drill string is modeled as a distributed wave equation coupled with Ordinary Differential Equations (ODEs) at the boundaries which represent
Aarsnes, Ulf Jakob F., Auriol, Jean, Di Meglio, Florent, Shor, Roman   +3 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Puzzling Collapse of Electronic Sliding Friction on a Superconductor Surface

, 1998
In a recent paper [Phys. Rev. Lett. 80 (1998) 1690], Krim and coworkers have observed that the friction force, acting on a thin physisorbed layer of N_2 sliding on a lead film, abruptly decreases by a factor of ~2 when the lead film is cooled below its ...
B.N.J Persson, Cieplak, Dayo, E Tosatti, Krim, Krim, Persson, Persson, Persson, Persson, Persson, Sokoloff, Tomassone, Tomassone   +13 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Drag reduction by polymer additives from turbulent spectra [PDF]

, 2010
We extend the analysis of the friction factor for turbulent pipe flow reported by G. Gioia, P. Chakraborty and N. Goldenfeld (GCG) (G. Gioia and P. Chakraborty, Phys. Rev. Lett. 96, 044502 (2006), N. Goldenfeld, Phys. Rev. Lett. 96, 044503 (2006)) to the
Calzetta, Esteban
core   +2 more sources