Results 101 to 110 of about 18,461 (227)
Inflammation and mechanical force‐induced bone remodeling
Periodontology 2000, EarlyView.Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
BMC Evolutionary Biology, 2008 Background G protein-coupled receptors (GPCRs) are one of the largest families of genes in mammals. Branchiostoma floridae (amphioxus) is one of the species most closely related species to vertebrates.
Schiöth Helgi B +2 more
doaj +1 more source
The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases [PDF]
, 1998 Yu Katherine Xu, Roel Nusse
openalex +1 more source
International Journal of Cancer, Volume 157, Issue 3, Page 559-572, 1 August 2025.What's new? Too often, children treated for B‐cell acute lymphocytic leukemia (B‐ALL) experience relapse. Here, the authors investigate the role of dyslipidemia in leukemia progression. Higher adipogenicity in bone marrow mesenchymal stem cells, and increased triglyceride accumulation, are associated with higher risk of death.
Lili Song +10 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.Effect of lobaric acid on Wnt/β‐catenin pathway in breast cancer. ABSTRACT Lichen secondary metabolites with many remarkable biological activities are used in cancer treatments due to their low side effects and high anticancer potential. In particular, these metabolites constitute an interesting research area in cancer treatments due to their potential
Şeyda Nur Kalın +6 more
wiley +1 more source
Identification of a Novel Functional Non-synonymous Single Nucleotide Polymorphism in Frizzled Class Receptor 6 Gene for Involvement in Depressive Symptoms [PDF]
, 2022 Haijun Han +7 more
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In silico analyses of Wnt1 nsSNPs reveal structurally destabilizing variants, altered interactions with Frizzled receptors and its deregulation in tumorigenesis. [PDF]
Sci Rep, 2022 Mondal A +4 more
europepmc +1 more source
British Journal of Pharmacology, Volume 182, Issue 14, Page 3044-3067, July 2025.Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Cell Reports, 2021 Summary: WNTs play key roles in development and disease, signaling through Frizzled (FZD) seven-pass transmembrane receptors and numerous co-receptors including ROR and RYK family receptor tyrosine kinases (RTKs).
Fumin Shi +12 more
doaj
Localization of Disulfide Bonds in the Frizzled Module of Ror1 Receptor Tyrosine Kinase [PDF]
, 2001 Emőke Roszmusz +3 more
openalex +1 more source