Results 101 to 110 of about 19,373 (224)

Mutations in Frizzled Class Receptor 4 Associated With Congenital Cavus Foot Deformity [PDF]

, 2021
Wenjin Yan, Haijun Mao, Xingquan Xu, Liming Zheng, Pengjun Yu, Dai Jin, Guangyue Xu, Qing Jiang, Yannick Yang   +8 more
openalex   +1 more source

Placental Protein Release and Uptake From the Fetal Circulation in Healthy Term Pregnancies—A Human In Vivo Exploratory Study

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Fetal‐placental communication was explored by comparing protein abundances in paired umbilical artery and vein samples, using the SomaLogic 5000‐plex platform. 766 proteins were identified as released by the placenta, largely supported by placental gene expression patterns reported in transcriptomic studies.
Hilde Bastøe Sellevoll, Ina Jungersen Andresen, Ane Cecilie Westerberg, Maren‐Helene Langeland Degnes, Thor Ueland, Manuela Zucknick, Trond Melbye Michelsen   +6 more
wiley   +1 more source

TIMP2 promotes AKI‐CKD transition by inducing tubular maladaptive repair and cell senescence via targeting Wnt/β‐catenin signalling

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
1. TIMP2 is upregulated in injured renal tubules and promotes maladaptive repair and cell senescence. 2. Genetic deletion of TIMP2 in tubular epithelial cells attenuates renal fibrosis and improves mitochondrial function. 3. TIMP2 activates Wnt/β‐catenin signalling by binding to LRP6 via an MMP‐independent mechanism.
Dongxue Xu, Haichuan Yu, Jingjing Pang, Xiaoyu Zhang, Jun Jiang, Yiming Li, Zhiyong Peng   +6 more
wiley   +1 more source

Distinct Frizzled receptors independently mediate endomesoderm specification and primary archenteron invagination during gastrulation in Nematostella

, 2021
Naveen Wijesena, Hongyan Sun, Shalika Kumburegama, Athula H. Wikramanayake   +3 more
openalex   +2 more sources

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Multiple Wnts and Frizzled Receptors Regulate Anteriorly Directed Cell and Growth Cone Migrations in Caenorhabditis elegans [PDF]

, 2006
Chun‐Liang Pan, James Endres Howell, Scott G. Clark, Massimo A. Hilliard, Shaun Cordes, Cornelia I. Bargmann, Gian Garriga   +6 more
openalex   +1 more source

Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes

International Journal for Parasitology: Drugs and Drug Resistance, 2018
G protein-coupled receptors (GPCRs) are established drug targets. Despite their considerable appeal as targets for next-generation anthelmintics, poor understanding of their diversity and function in parasitic helminths has thwarted progress towards GPCR-
Paul McVeigh, Erin McCammick, Paul McCusker, Duncan Wells, Jane Hodgkinson, Steve Paterson, Angela Mousley, Nikki J. Marks, Aaron G. Maule   +8 more
doaj   +1 more source

In silico analyses of Wnt1 nsSNPs reveal structurally destabilizing variants, altered interactions with Frizzled receptors and its deregulation in tumorigenesis. [PDF]

Sci Rep, 2022
Mondal A, Paul D, Dastidar SG, Saha T, Goswami AM.   +4 more
europepmc   +1 more source

Sea anemone Frizzled receptors play partially redundant roles in the oral-aboral axis patterning

, 2022
Isabell Niedermoser, Tatiana Lebedeva, Grigory Genikhovich   +2 more
openalex   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source