Results 91 to 100 of about 29,955 (198)
Advanced Science, Volume 13, Issue 16, 18 March 2026.An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz +10 more
wiley +1 more source
LifeThe effectiveness of acyclovir, a selective anti-herpesvirus agent, was tested both in silico and in vitro against two ranaviruses, namely the European catfish virus (ECV) and Frog virus 3 (FV3).
Richárd Rácz +3 more
doaj +1 more source
PLoS ONE, 2020 Pathogen-host interactions are important components of epidemiological research, but are scarcely investigated in chelonians. Red-eared sliders (Trachemys scripta elegans), are recognized as a model for frog virus-3 infection (FV3), a ranavirus in the ...
Jeremy M Rayl, Matthew C Allender
doaj +1 more source
Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors. [PDF]
, 2009 Protein kinase PKR (also known as EIF2AK2) is activated during viral infection and phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF2), leading to inhibition of translation and viral replication. We report fast evolution
Dever, Thomas E +4 more
core
Adaptive immunity and histopathology in frog virus 3-infected Xenopus
Virology, 2005 Xenopus has been used as an experimental model to evaluate the contribution of adaptive cellular immunity in amphibian host susceptibility to the emerging ranavirus FV3. Conventional histology and immunohistochemistry reveal that FV3 has a strong tropism for the proximal tubular epithelium of the kidney and is rarely disseminated elsewhere in Xenopus ...
Robert, Jacques +5 more
openaire +2 more sources
Viruses, 2019 Ranaviruses are the second deadliest pathogens for amphibian populations throughout the world. Despite their wide distribution in America, these viruses have never been reported in Mexico, the country with the fifth highest amphibian diversity in the ...
Bernardo Saucedo +8 more
doaj +1 more source
The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV) [PDF]
, 2013 In contrast to typical mammals, the chicken MHC (the BF-BL region of the B locus) has strong genetic associations with resistance and susceptibility to infectious pathogens as well as responses to vaccines.
Butter, Colin +4 more
core +1 more source
Frog virus 3 requires RNA polymerase II for its replication [PDF]
Journal of Virology, 1981 The involvement of host cell RNA polymerase II in the replication of frog virus 3 (FV 3) was examined in alpha-amanitin-sensitive or -resistant Chinese hamster ovary (CHO) cells in the presence and absence of alpha-amanitin. In the presence of alpha-amanitin, FV 3 replicated normally in resistant CHO cells but failed to do so in sensitive CHO cells ...
openaire +2 more sources
Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity [PDF]
, 2016 Citation: Sang, Y. M., Liu, Q. F., Lee, J., Ma, W. J., McVey, D. S., & Blecha, F. (2016). Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity. Scientific Reports, 6, 17.
Blecha, Frank +5 more
core +1 more source
Quantifying microbiota impact on plant traits for the guidance of breeding programs
New Phytologist, EarlyView.
Manuel Blouin +5 more
wiley +1 more source