Results 211 to 220 of about 98,352 (316)
White matter hyperintensities precede other biomarkers in GRN frontotemporal dementia [PDF]
Soltaninejad, Mahdie +38 more
openalex
Hereditary Frontotemporal Dementia Caused by Tau Gene Mutations
John C. van Swieten +1 more
openalex +2 more sources
Serum neurofilament light chain in behavioral variant frontotemporal dementia [PDF]
Petra Steinacker +52 more
openalex +1 more source
A complex network perspective on brain disease
ABSTRACT If brain anatomy and dynamics have a complex network structure as it has become standard to posit, it is reasonable to assume that such a structure should play a key role not only in brain function but also in brain dysfunction. However, exactly how network structure is implicated in brain damage and whether at least some pathologies can be ...
David Papo, Javier M. Buldú
wiley +1 more source
ABSTRACT Background People with Down syndrome (DS) have a strong genetic predisposition to Alzheimer's disease (AD). However, the clinical burden and associated risk factors in diverse, non‐Western populations remain less understood. This study aimed to investigate the prevalence of dementia in Japanese adults with DS and to identify modifiable ...
Shintaro Takenoshita +6 more
wiley +1 more source
False Reports from Patients with Frontotemporal Dementia: Delusions or Confabulations? [PDF]
Mario F. Mendez +3 more
openalex +1 more source
Analyses of the Effects of Wild‐Type TDP‐43 Overexpression in Oxytocin Neurons in Mice
ABSTRACT Selective TDP‐43 overexpression in oxytocin neurons in the paraventricular nucleus of the hypothalamus causes a decrease in oxytocin‐immunopositive cells compared to uninjected mice. AAV‐mediated TDP‐43 overexpression in oxytocin neurons does not appear to be a major driver of behavioural and metabolic phenotypes in mice.
Sofia Bergh +2 more
wiley +1 more source
Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory [PDF]
et al,, Fagan, Anne M, Jerome, Gina
core +1 more source
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) characterized by progressive degeneration of both upper and lower motor neurons, along with skeletal muscles innervated by them. The identification of key molecules involved in disease pathology remains crucial for ALS, as no curative treatment is currently available ...
Paloma Martínez‐Alesón +3 more
wiley +1 more source
TDP‐43 overexpressing mice, a genetic model of frontotemporal dementia, exhibit dramatic changes in their small intestinal endocannabinoidome members, in terms of both altered concentrations of lipid mediators and expression of some of their receptors (Cnr1, Gpr119, Gpr55, Pparg) and metabolic enzymes (Napepld, Faah). Also, the levels of some oxylipins
Hayatte‐Dounia Mir +9 more
wiley +1 more source

